MeSH Browser

MeSH Heading: Receptors, Neurokinin-1
Tree Number(s): D12.776.543.750.695.862.500; D12.776.543.750.720.600.830.500; D12.776.543.750.750.555.830.500
Unique ID: D018040
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018040
Scope Note: A class of cell surface receptors for TACHYKININS with a preference for SUBSTANCE P. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral neurons, smooth muscle cells, acinar cells, endothelial cells, fibroblasts, and immune cells.
Entry Version: RECEPT NEUROKININ 1
Entry Term(s): NK-1 Receptor; NK-1 Receptors; Neurokinin-1 Receptor; Neurokinin-1 Receptors; Receptors, NK-1; Receptors, SP-P; Receptors, Substance P; SP-P Receptor; SP-P Receptors; Substance P Receptor; Substance P Receptors; Substance-P Receptor; Tachykinin Receptor 1
Previous Indexing: Receptors, Cell Surface (1981-1984); Receptors, Drug (1968-1993); Receptors, Neurotransmitter (1985-1993)
Public MeSH Note: 94; SUBSTANCE P RECEPTOR was indexed under RECEPTORS, SYNAPTIC 1985-93 & RECEPTORS, ENDOGENOUS SUBSTANCES 1981-84
Online Note: use RECEPTORS, NEUROKININ-1 (NM) to search SUBSTANCE P RECEPTOR 1981-93
History Note: 94; was SUBSTANCE P RECEPTOR (NM) 1981-93; NK-1 RECEPTOR & NEUROKININ-1 RECEPTOR were SY to SUBSTANCE K RECEPTOR 1986-93; NK-1 RECEPTOR SITE was SY to TACHYKININ RECEPTOR 1989-93
Entry Combination: antagonists & inhibitors:Neurokinin-1 Receptor Antagonists
Date Established: 1994/01/01
Date of Entry: 1993/06/21
Revision Date: 2016/06/17

Entry Combination: antagonists & inhibitors:Neurokinin-1 Receptor Antagonists
Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, G-Protein-Coupled [D12.776.543.750.695]
        
        Receptors, Tachykinin [D12.776.543.750.695.862]
        
        Receptors, Neurokinin-1 [D12.776.543.750.695.862.500]
        
        Receptors, Neurokinin-2 [D12.776.543.750.695.862.540]
        
        Receptors, Neurokinin-3 [D12.776.543.750.695.862.580]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Neurotransmitter [D12.776.543.750.720]
        
        Receptors, Neuropeptide [D12.776.543.750.720.600]
        
        Receptors, Tachykinin [D12.776.543.750.720.600.830]
        
        Receptors, Neurokinin-1 [D12.776.543.750.720.600.830.500]
        
        Receptors, Neurokinin-2 [D12.776.543.750.720.600.830.540]
        
        Receptors, Neurokinin-3 [D12.776.543.750.720.600.830.580]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Peptide [D12.776.543.750.750]
        
        Receptors, Neuropeptide [D12.776.543.750.750.555]
        
        Receptors, Tachykinin [D12.776.543.750.750.555.830]
        
        Receptors, Neurokinin-1 [D12.776.543.750.750.555.830.500]
        
        Receptors, Neurokinin-2 [D12.776.543.750.750.555.830.540]
        
        Receptors, Neurokinin-3 [D12.776.543.750.750.555.830.580]

Receptors, Neurokinin-1 Preferred

Concept UI: M0027226
Scope Note: A class of cell surface receptors for TACHYKININS with a preference for SUBSTANCE P. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral neurons, smooth muscle cells, acinar cells, endothelial cells, fibroblasts, and immune cells.
Terms: Receptors, Neurokinin-1 Preferred Term
Term UI T053947
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1994); Substance P Receptors
Term UI T053940
Date12/29/1992
LexicalTag NON
ThesaurusID NLM (1994); Receptors, Substance P
Term UI T053941
Date05/06/1993
LexicalTag NON
ThesaurusID NLM (1994); NK-1 Receptor
Term UI T053942
Date12/29/1992
LexicalTag NON
ThesaurusID NLM (1994); Receptors, NK-1
Term UI T053943
Date04/19/1993
LexicalTag NON
ThesaurusID NLM (1994); NK-1 Receptors
Term UI T053944
Date12/29/1992
LexicalTag NON
ThesaurusID NLM (1994); Neurokinin-1 Receptor
Term UI T053945
Date12/29/1992
LexicalTag NON
ThesaurusID NLM (1994); Neurokinin-1 Receptors
Term UI T053946
Date12/29/1992
LexicalTag NON
ThesaurusID NLM (1994); Receptors, SP-P
Term UI T053948
Date04/19/1993
LexicalTag NON
ThesaurusID NLM (1994); SP-P Receptor
Term UI T053949
Date12/29/1992
LexicalTag NON
ThesaurusID NLM (1994); SP-P Receptors
Term UI T053950
Date12/29/1992
LexicalTag NON
ThesaurusID NLM (1994); Substance-P Receptor
Term UI T840391
Date04/12/2013
LexicalTag NON
ThesaurusID NLM (2014); Substance P Receptor
Term UI T053939
Date12/29/1992
LexicalTag NON
ThesaurusID NLM (1994); Tachykinin Receptor 1
Term UI T840392
Date04/12/2013
LexicalTag NON
ThesaurusID NLM (2014)

Receptors, Neurokinin-1 MeSH Descriptor Data 2024