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Hexamethonium MeSH Descriptor Data 2024


MeSH Heading
Hexamethonium
Tree Number(s)
D02.092.877.250.592.400
D02.675.276.558.592.500
Unique ID
D018738
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018738
Scope Note
A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.
Entry Term(s)
Depressin
Hexamethonium Bitartrate
Hexamethonium Bromide
Hexamethonium Chloride
Hexamethonium Dibromide
Hexamethonium Dibromide Dihydrate
Hexamethonium Dichloride Dihydrate
Hexamethonium Dihydroxide
Hexamethonium Diiodide
Hexamethonium Dimethylsulfate
Hexamethonium Diperchlorate
Hexamethonium Iodide
Hexamethonium Monotartrate
Hexonium
Pharm Action
Antihypertensive Agents
Ganglionic Blockers
Nicotinic Antagonists
Registry Number
3C9PSP36Z2
Related Numbers
16986-49-5
2079-78-9
5187-74-6
55-97-0
556-81-0
56503-18-5
60-25-3
60-26-4
78995-78-5
815-76-9
870-62-2
8J77X3S603
G2753KSN40
TIV4Q933FU
CAS Type 1 Name
1,6-hexanediaminium, N,N,N,N',N',N'-hexamethyl-
Previous Indexing
Hexamethonium Compounds (1980-1994)
Public MeSH Note
95; HEXAMETHONIUM was indexed under HEXAMETHONIUM COMPOUNDS 1980-94
Online Note
use HEXAMETHONIUM (NM) to search HEXAMETHONIUM 1980-94
History Note
95; was HEXAMETHONIUM (NM) 1980-94
Entry Combination
analogs & derivatives:Hexamethonium Compounds
Date Established
1995/01/01
Date of Entry
1994/06/01
Revision Date
2013/07/08
Hexamethonium Preferred
Hexamethonium Dihydroxide Narrower
Hexamethonium Diiodide Narrower
Hexamethonium Dimethylsulfate Narrower
Hexamethonium Diperchlorate Narrower
Hexamethonium Iodide Narrower
Hexamethonium Dibromide Dihydrate Narrower
Depressin Narrower
Hexamethonium Bitartrate Narrower
Hexamethonium Bromide Narrower
Hexamethonium Chloride Narrower
Hexamethonium Dibromide Narrower
Hexamethonium Dichloride Dihydrate Narrower
Hexamethonium Monotartrate Narrower
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