MeSH Browser

MeSH Heading: Polymorphism, Single-Stranded Conformational
Tree Number(s): G05.365.795.600
Unique ID: D018807
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D018807
Annotation: POLYMORPHISM, SINGLE NUCLEOTIDE is also available
Scope Note: Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
Entry Term(s): SSCP; Single-Stranded Conformational Polymorphism
Previous Indexing: Polymorphism (Genetics) (1990-1994)
Public MeSH Note: 1995
History Note: 1995
Date Established: 1995/01/01
Date of Entry: 1994/05/31
Revision Date: 2008/07/08

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Concept UI: M0028160
Scope Note: Variation in a population's DNA sequence that is detected by determining alterations in the conformation of denatured DNA fragments. Denatured DNA fragments are allowed to renature under conditions that prevent the formation of double-stranded DNA and allow secondary structure to form in single stranded fragments. These fragments are then run through polyacrylamide gels to detect variations in the secondary structure that is manifested as an alteration in migration through the gels.
Terms: Polymorphism, Single-Stranded Conformational Preferred Term
Term UI T056036
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1995); Single-Stranded Conformational Polymorphism
Term UI T056035
Date04/25/1994
LexicalTag NON
ThesaurusID NLM (1995); SSCP
Term UI T056037
Date03/24/1994
LexicalTag ABB
ThesaurusID NLM (1995)

Polymorphism, Single-Stranded Conformational MeSH Descriptor Data 2024