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Pharmacogenomic Variants MeSH Descriptor Data 2023


MeSH Heading
Pharmacogenomic Variants
Tree Number(s)
G05.365.795.446
Unique ID
D000071184
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071184
Scope Note
Naturally occurring genetic variations associated with drug response (e.g., dosage, extent and rate of metabolic processes). While these variants are not markers for GENETIC PREDISPOSITION TO DISEASE they influence PHARMACOKINETICS and pharmacodynamics and often occur on genes encoding drug metabolism enzymes and transporters (e.g., ANGIOTENSIN CONVERTING ENZYME; CYTOCHROME P-450 CYP2D6).
Entry Term(s)
Pharmacogenetic Variants
Pharmacokinetic Genetic Variants
Previous Indexing
Genetic Variation (1968-2016)
Pharmacogenetics (1968-2016)
Polymorphism, Genetic (1980-2016)
See Also
Pharmacogenetics
Precision Medicine
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/01/20
Pharmacogenomic Variants Preferred
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