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A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.
Entry Term(s)
CCL2 Chemokine
Chemokine (C-C Motif) Ligand 2
Chemokines CCL2
Monocyte Chemoattractant Protein-1
Monocyte Chemotactic Protein-1
Monocyte Chemotactic and Activating Factor
Registry Numbers
0
Previous Indexing
Chemotactic Factors (1989-1995)
Glycoproteins (1988-1990)
Public MeSH Note
2007; see MONOCYTE CHEMOATTRACTANT PROTEIN-1 1996-2006; MONOCYTE CHEMOTACTIC AND ACTIVATING FACTOR was indexed under CHEMOTACTIC FACTORS 1991-1995 & GLYCOPROTEINS 1988-1990
A chemokine that is a chemoattractant for MONOCYTES and may also cause cellular activation of specific functions related to host defense. It is produced by LEUKOCYTES of both monocyte and lymphocyte lineage and by FIBROBLASTS during tissue injury. It has specificity for CCR2 RECEPTORS.