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Troponin I MeSH Descriptor Data 2022


MeSH Heading
Troponin I
Tree Number(s)
D05.500.945.925
D05.750.078.730.825.925
D12.776.210.500.910.925
D12.776.220.525.825.925
Unique ID
D019210
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019210
Annotation
TROPONIN C & TROPONIN T are also available
Scope Note
A TROPONIN complex subunit that inhibits ACTOMYOSIN ATPASE activity thereby disrupting ACTIN and MYOSIN interaction. There are three troponin I subtypes: troponin I1, I2 and I3. Troponin I3 is cardiac-specific whereas troponin I1 and I2 are skeletal subtypes. Troponin I3 is a BIOMARKER for damaged or injured CARDIAC MYOCYTES and mutations in troponin I3 gene are associated with FAMILIAL HYPERTROPHIC CARDIOMYOPATHY.
Entry Term(s)
Troponin I1
Troponin I2
Troponin I3
Troponin-I
Registry Number
0
Previous Indexing
Muscle Proteins (1975-1978)
Troponin (1979-1996)
Public MeSH Note
97; TROPONIN I was indexed under TROPONIN 1979-96 & MUSCLE PROTEINS 1975-78
Online Note
use TROPONIN I (NM) to search TROPONIN I 1980-96
History Note
97; was TROPONIN I (NM) 1975-96
Date Established
1997/01/01
Date of Entry
1996/06/10
Revision Date
2016/07/06
Troponin I Preferred
Troponin I3 Narrower
Troponin I2 Narrower
Troponin I1 Narrower
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