Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NLM Logo

Phosphatidylinositol 4,5-Diphosphate MeSH Descriptor Data 2025


MeSH Heading
Phosphatidylinositol 4,5-Diphosphate
Tree Number(s)
D10.570.755.375.760.400.942.625.900
Unique ID
D019269
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019269
Scope Note
A phosphoinositide present in all eukaryotic cells, particularly in the plasma membrane. It is the major substrate for receptor-stimulated phosphoinositidase C, with the consequent formation of inositol 1,4,5-triphosphate and diacylglycerol, and probably also for receptor-stimulated inositol phospholipid 3-kinase. (Kendrew, The Encyclopedia of Molecular Biology, 1994)
Entry Term(s)
Phosphatidylinositol 4,5-Biphosphate
Phosphatidylinositol Phosphate, PtdIns(4,5)P2
Phosphatidylinositol-4,5-Biphosphate
PtIns 4,5-P2
PtdIns(4,5)P2
PtdInsP
PtdInsP2
Registry Numbers
0
Previous Indexing
Phosphatidylinositol Phosphates (1994-1996)
Phosphatidylinositols (1981-1993)
Public MeSH Note
97; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE was indexed under PHOSPHATIDYLINOSITOL PHOSPHATES 1994-96 & PHOSPHOINOSITIDES 1981-93
Online Note
use PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE (NM) to search PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE 1981-96
History Note
97; see PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE (NM) 1981-96
Date Established
1997/01/01
Date of Entry
1996/06/10
Revision Date
2010/06/25
Phosphatidylinositol 4,5-Diphosphate Preferred
page delivered in 0.137s