MeSH Browser

MeSH Heading: Heparin Lyase
Tree Number(s): D08.811.520.241.700.512
Unique ID: D019763
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019763
Scope Note: An enzyme of the isomerase class that catalyzes the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. (From Enzyme Nomenclature, 1992) EC 4.2.2.7.
Entry Term(s): Heparin Eliminase; Heparinase; Heparinase I; Neutralase
CAS Type 1 Name: heparin lyase
Previous Indexing: Heparin (1973-1982); Lyases (1973-1979); Polysaccharide-Lyases (1975-1997)
Public MeSH Note: 98; HEPARIN LYASE was indexed under POLYSACCHARIDE-LYASES 1975-97, HEPARIN 1973-82 & LYASES 1973-79
History Note: 98; use HEPARIN LYASE (NM) 1973-97
Date Established: 1998/01/01
Date of Entry: 1997/06/25
Revision Date: 2016/06/28

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0029324
Scope Note: An enzyme of the isomerase class that catalyzes the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends. (From Enzyme Nomenclature, 1992) EC 4.2.2.7.
Terms: Heparin Lyase Preferred Term
Term UI T058746
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1998); Heparin Eliminase
Term UI T058747
Date11/27/1996
LexicalTag NON
ThesaurusID NLM (1998); Heparinase
Term UI T058748
Date11/27/1996
LexicalTag NON
ThesaurusID NLM (1998); Heparinase I
Term UI T058749
Date11/27/1996
LexicalTag NON
ThesaurusID NLM (1998); Neutralase
Term UI T058750
Date11/27/1996
LexicalTag NON
ThesaurusID NLM (1998)

Heparin Lyase MeSH Descriptor Data 2024