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2,3-Diphosphoglycerate MeSH Descriptor Data 2023


MeSH Heading
2,3-Diphosphoglycerate
Tree Number(s)
D02.241.081.844.387.388.175
D02.241.511.902.387.388.175
D02.705.400.140.175
D09.811.366.388.175
Unique ID
D019794
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019794
Scope Note
A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
Entry Term(s)
2,3-Bisphosphoglycerate
2,3-DPG
2,3-Diphosphoglycerate, (D)-Isomer
2,3-Diphosphoglyceric Acid
Glycerate 2,3-Bisphosphate
Registry Number
138-81-8
Related Numbers
14438-19-8
Previous Indexing
Diphosphoglyceric Acids (1980-1997)
Public MeSH Note
98; 2,3-DIPHOSPHOGLYCERATE was indexed under DIPHOSPHOGLYCERIC ACIDS 1980-97
History Note
98; use 2,3-DIPHOSPHOGLYCERATE (NM) 1980-97
Entry Combination
analogs & derivatives:Diphosphoglyceric Acids
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2012/07/03
2,3-Diphosphoglycerate Preferred
2,3-Diphosphoglyceric Acid Broader
2,3-Diphosphoglycerate, (D)-Isomer Related
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