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15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid MeSH Descriptor Data 2024


MeSH Heading
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Tree Number(s)
D01.248.497.158.685.750.744.650.500.500
D01.339.431.374.744.650.500.500
D01.650.550.750.700.650.500.500
D02.389.593.374.744.650.500.500
D10.251.355.255.550.025.650.500.500
D23.469.050.175.725.025.650.500.500
D23.469.700.630.500
Unique ID
D019796
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019796
Scope Note
A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of VASOPRESSIN and activation of TYPE C PHOSPHOLIPASES. (From J Pharmacol Exp Ther 1983;224(1): 108-117; Biochem J 1984;222(1):103-110)
Entry Term(s)
(15S)-Hydroxy-11 alpha, 9 alpha-(epoxymethano)prosta-5Z, 13E-dienoic Acid
(15S)hydroxy-9alpha,11alpha-(epoxymethano)prosta-5,13-dienoic acid
11 alpha,9 alpha-Epoxymethano PGH2
9,11-Dideoxy-11 alpha,9 alpha-epoxymethanoprostaglandin F2 alpha
9,11-Dideoxy-11 alpha,9-alpha-epoxymethano-PGF2 alpha
9,11-epoxymethano-PGH2
U-44619
U-46619
U44619
U46619
Pharm Action
Vasoconstrictor Agents
Registry Number
76898-47-0
Related Numbers
56985-40-1-isomer
72580-47-3-isomer
87421-95-2-isomer
CAS Type 1 Name
5-Heptenoic Acid, 7-(6-(3-Hydroxy-1-Ocentyl)-2-Oxabicyclo(2.2.1)hept-5-yl)-, (1R-(1alpha,4alpha,5 beta(Z),6alpha(1E,3S*)))-
Previous Indexing
Prostaglandin Endoperoxides, Synthetic (1978-1997)
Thromboxane A2/analogs & derivatives (1983-1997)
Public MeSH Note
1998; 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID was indexed under PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC 1978-97 & THROMBOXANE A2/analogs & derivatives 1983-97; (15S)HYDROXY-9ALPHA,11ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID and 9,11-EPOXYMETHANO-PGH2 were indexed under PROSTAGLANDINS H 1993-2003 & PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC 1986-1992
History Note
1998; use 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID (NM) 1977-1997; for (15S)HYDROXY-9ALPHA,11ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID and 9,11-EPOXYMETHANO-PGH2 use PROSTAGLANDIN H2 (NM) 1992-2003
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2023/02/26
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid Preferred
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