MeSH Browser

MeSH Heading: Rhodamine 123
Tree Number(s): D03.633.300.953.600.500
Unique ID: D020112
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020112
Scope Note: A fluorescent probe with low toxicity which is a potent substrate for ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 and the bacterial multidrug efflux transporter. It is used to assess mitochondrial bioenergetics in living cells and to measure the efflux activity of ATP BINDING CASSETTE TRANSPORTER, SUBFAMILY B, MEMBER 1 in both normal and malignant cells. (Leukemia 1997;11(7):1124-30)
Pharm Action: Fluorescent Dyes
Registry Numbers: 1N3CZ14C5O
Related Numbers: 62669-70-9
CAS Type 1 Name: Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-, chloride
Previous Indexing: Rhodamines (1982-1998)
See Also: ATP Binding Cassette Transporter, Subfamily B, Member 1
Public MeSH Note: 1999; RHODAMINE 123 was indexed under RHODAMINES 1982-1998
History Note: 1999; use RHODAMINE 123 (NM) 1982-1998
Date Established: 1999/01/01
Date of Entry: 2024/08/09
Revision Date: 2024/05/31

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Rhodamine 123 MeSH Descriptor Data 2025