MeSH Browser

MeSH Heading: Dendritic Cells, Follicular
Tree Number(s): A10.549.400.500.200; A11.066.275; A15.382.066.275; A15.382.520.604.412.500.200
Unique ID: D020566
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020566
Annotation: DENDRITIC CELLS is also available
Scope Note: Non-hematopoietic cells, with extensive dendritic processes, found in the primary and secondary follicles of lymphoid tissue (the B cell zones). They are different from conventional DENDRITIC CELLS associated with T-CELLS. They are derived from MESENCHYMAL STEM CELLS and are negative for class II MHC antigen and do not process or present antigen like the conventional dendritic cells do. Instead, follicular dendritic cells have FC RECEPTORS and C3B RECEPTORS that hold antigen in the form of ANTIGEN-ANTIBODY COMPLEXES on their surfaces for long periods for recognition by B-CELLS.
Entry Term(s): Dendritic Reticulum Cells, Follicular; Follicular Dendritic Cells
Previous Indexing: Dendritic Cells (1987-1999); Lymph Nodes (1980-1986)
Public MeSH Note: 2000; see DENDRITIC CELLS 1987-1999
History Note: 2000; use DENDRITIC CELLS 1987-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2015/06/22

Allowable Qualifiers: chemistry (CH)

classification (CL)

cytology (CY)

drug effects (DE)

enzymology (EN)

immunology (IM)

metabolism (ME)

microbiology (MI)

parasitology (PS)

pathology (PA)

physiology (PH)

radiation effects (RE)

transplantation (TR)

ultrastructure (UL)

virology (VI)

Concept UI: M0328454
Scope Note: Non-hematopoietic cells, with extensive dendritic processes, found in the primary and secondary follicles of lymphoid tissue (the B cell zones). They are different from conventional DENDRITIC CELLS associated with T-CELLS. They are derived from MESENCHYMAL STEM CELLS and are negative for class II MHC antigen and do not process or present antigen like the conventional dendritic cells do. Instead, follicular dendritic cells have FC RECEPTORS and C3B RECEPTORS that hold antigen in the form of ANTIGEN-ANTIBODY COMPLEXES on their surfaces for long periods for recognition by B-CELLS.
Terms: Dendritic Cells, Follicular Preferred Term
Term UI T010882
Date06/19/1986
LexicalTag NON
ThesaurusID UNK (19XX); Follicular Dendritic Cells
Term UI T361719
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Dendritic Reticulum Cells, Follicular
Term UI T690674
Date02/01/2007
LexicalTag NON
ThesaurusID NLM (2008)

Dendritic Cells, Follicular MeSH Descriptor Data 2024