MeSH Browser

MeSH Heading: alpha-Tocopherol
Tree Number(s): D03.383.663.283.909.750.249; D03.633.100.150.909.750.249
Unique ID: D024502
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D024502
Annotation: deficiency: coordinate ALPHA-TOCOPHEROL with VITAMIN E DEFICIENCY
Scope Note: A natural tocopherol and one of the most potent antioxidant tocopherols. It exhibits antioxidant activity by virtue of the phenolic hydrogen on the 2H-1-benzopyran-6-ol nucleus. It has four methyl groups on the 6-chromanol nucleus. The natural d form of alpha-tocopherol is more active than its synthetic dl-alpha-tocopherol racemic mixture.
Entry Term(s): 3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ol; R,R,R-alpha-Tocopherol; Tocopherol Acetate; Tocopherol Succinate; Tocopheryl Acetate; Vitamin E Succinate; alpha-Tocopherol Acetate; alpha-Tocopherol Hemisuccinate; alpha-Tocopherol Succinate; alpha-Tocopheryl Calcium Succinate; d-alpha Tocopherol; d-alpha-Tocopheryl Acetate
Pharm Action: Antioxidants
Vitamins
Registry Number: H4N855PNZ1
Related Numbers: 17407-37-3; 58-95-7; 59-02-9; 9E8X80D2L0; LU4B53JYVE; N9PR3490H9
Previous Indexing: Vitamin E (1965-2001)
Public MeSH Note: 2002; see VITAMIN E 1966-2001; ALPHA-TOCOPHEROL SUCCINATE was indexed under VITAMIN E 1985-2008; ALPHA-TOCOPHEROL ACETATE was indexed under ALPHA-TOCOPHEROL 1980-2008, for TOCOPHEROL ACETATE, D-ALPHA-TOCOPHEROL ACETATE, and TOCOPHEROL SUCCINATE see TOCOPHEROLS 2008-2013
History Note: 2002; use VITAMIN E 1966-2001; for ALPHA-TOCOPHEROL SUCCINATE use VITAMIN E 1982-2007; for TOCOPHEROL ACETATE, D-ALPHA-TOCOPHEROL ACETATE, and TOCOPHEROL SUCCINATE use TOCOPHEROLS 2008-2013
Date Established: 2002/01/01
Date of Entry: 2001/07/25
Revision Date: 2018/07/02

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, 1-Ring [D03.383]
  - Pyrans [D03.383.663]
    - Benzopyrans [D03.383.663.283]
      - Vitamin E [D03.383.663.283.909]
        
        Tocopherols [D03.383.663.283.909.750]
        
        alpha-Tocopherol [D03.383.663.283.909.750.249]
        
        beta-Tocopherol [D03.383.663.283.909.750.374]
        
        gamma-Tocopherol [D03.383.663.283.909.750.500]

Heterocyclic Compounds [D03]
- Heterocyclic Compounds, Fused-Ring [D03.633]
  - Heterocyclic Compounds, 2-Ring [D03.633.100]
    - Benzopyrans [D03.633.100.150]
      - Vitamin E [D03.633.100.150.909]
        
        Tocopherols [D03.633.100.150.909.750]
        
        alpha-Tocopherol [D03.633.100.150.909.750.249]
        
        beta-Tocopherol [D03.633.100.150.909.750.374]
        
        gamma-Tocopherol [D03.633.100.150.909.750.500]

alpha-Tocopherol Preferred

d-alpha Tocopherol Narrower

alpha-Tocopherol Succinate Narrower

Concept UI: M0104481
Registry Number: LU4B53JYVE
Terms: alpha-Tocopherol Succinate Preferred Term
Term UI T709566
Date11/14/2007
LexicalTag NON
ThesaurusID; Tocopherol Succinate
Term UI T709659
Date11/15/2007
LexicalTag NON
ThesaurusID; alpha-Tocopherol Hemisuccinate
Term UI T709652
Date11/15/2007
LexicalTag NON
ThesaurusID NLM (2009); Vitamin E Succinate
Term UI T000943243
Date05/23/2018
LexicalTag NON
ThesaurusID NLM (2017)

d-alpha-Tocopheryl Acetate Related

alpha-Tocopherol Acetate Narrower

alpha-Tocopheryl Calcium Succinate Narrower

alpha-Tocopherol MeSH Descriptor Data 2024