NLM Logo

Polyadenylation MeSH Descriptor Data 2022


MeSH Heading
Polyadenylation
Tree Number(s)
G02.111.760.225.710
G03.839.225.710
G05.308.700.225.710
Unique ID
D026723
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D026723
Scope Note
The addition of a tail of polyadenylic acid (POLY A) to the 3' end of mRNA (RNA, MESSENGER). Polyadenylation involves recognizing the processing site signal, (AAU‌AAA), and cleaving of the mRNA to create a 3' OH terminal end to which poly A polymerase (POLYNUCLEOTIDE ADENYLYLTRANSFERASE) adds 60-200 adenylate residues. The 3' end processing of some messenger RNAs, such as histone mRNA, is carried out by a different process that does not include the addition of poly A as described here.
Entry Term(s)
Previous Indexing
Poly A/metabolism (1975-2001)
RNA, Messenger/metabolism (1974-2001)
Public MeSH Note
2002
History Note
2002
Date Established
2002/01/01
Date of Entry
2001/07/25
Revision Date
2016/06/23
Polyadenylation Preferred
page delivered in 0.151s