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A class of animal lectins that bind specifically to beta-galactoside in a calcium-independent manner. Members of this class are distiguished from other lectins by the presence of a conserved carbohydrate recognition domain. The majority of proteins in this class bind to sugar molecules in a sulfhydryl-dependent manner and are often referred to as S-type lectins, however this property is not required for membership in this class.
Entry Term(s)
D-Galactoside-Binding Lectin
Galactose-Binding Lectin
Galaptins
Galectin
Lectins, S-Type
S-Type Lectin
S-Type Lectins
beta-D-Gal(1-3)D-GalNAc Specific Lectins
beta-D-Galactosyl-Specific Lectin
beta-Galactoside Binding Lectin
Registry Numbers
0
Previous Indexing
Hemagglutinins (1978-2002)
Public MeSH Note
2003; GALAPTINS (now GALECTINS) was indexed under HEMAGGLUTININS 1978-2002
A class of animal lectins that bind specifically to beta-galactoside in a calcium-independent manner. Members of this class are distiguished from other lectins by the presence of a conserved carbohydrate recognition domain. The majority of proteins in this class bind to sugar molecules in a sulfhydryl-dependent manner and are often referred to as S-type lectins, however this property is not required for membership in this class.