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Calgranulin A MeSH Descriptor Data 2025


MeSH Heading
Calgranulin A
Tree Number(s)
D12.776.157.125.750.500.100
D12.776.631.658.750.500
D23.050.301.562.100
Unique ID
D040501
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D040501
Scope Note
A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.
Entry Term(s)
60B8-B Antigen
CABP-P8
Cystic Fibrosis Antigen
Leukocyte L1 Protein Light Chain
MRP-8 Protein
MRP8 Protein
Macrophage-Related Protein-8
Myeloid Calcium-Binding Protein P8
S100 A8 Protein
S100A8 Protein
Registry Numbers
0
Previous Indexing
Antigens, Differentiation (1989-2002)
Calcium-Binding Proteins (1989-2002)
Public MeSH Note
2003; CALGRANULIN A was indexed under CALCIUM-BINDING BINDING PROTEINS 1989-2002; MRP-8 PROTEIN (now CALGRANULIN A) was indexed under ANTIGENS, DIFFERENTIATION & CALCIUM-BINDING PROTEINS 1989-2002
History Note
2003; use CALGRANULIN A (NM) 1998-2002;
Date Established
2003/01/01
Date of Entry
2002/07/02
Revision Date
2023/06/09
Calgranulin A Preferred
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