The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.
Registry Numbers
0
Previous Indexing
Angiogenesis Factor (2003)
Membrane Glycoproteins (1997-2003)
Public MeSH Note
2004; ANGIOPOIETIN-1 was indexed under MEMBRANE GLYCOPROTEINS 1997-2003 & ANGIOGENESIS FACTOR 2003
The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.
