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Estrogenic Steroids, Alkylated MeSH Descriptor Data 2022


MeSH Heading
Estrogenic Steroids, Alkylated
Tree Number(s)
D06.472.334.851.437.968
Unique ID
D042782
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D042782
Scope Note
Estrogenic STEROIDS with aliphatic hydrocarbon chain substitution on C17 or other position. 17-alpha-ALKYLATION renders the molecule more stable, resistant to metabolic degradation, and improves oral efficacy. Examples of synthetic alkyl estrogens include ETHINYL ESTRADIOL and MESTRANOL. Substitutions at other sites generates antiestrogenic and cytotoxic properties.
Entry Term(s)
Alkyl Estrogenic Steroids
Alkylated Estrogenic Steroids
Pharm Action
Estrogens
Registry Number
0
Previous Indexing
Ethinyl Estradiol (1968-2003)
Public MeSH Note
2004
History Note
2004
Date Established
2004/01/01
Date of Entry
2003/07/09
Estrogenic Steroids, Alkylated Preferred
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