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Phosphatidylinositol Diacylglycerol-Lyase MeSH Descriptor Data 2022


MeSH Heading
Phosphatidylinositol Diacylglycerol-Lyase
Tree Number(s)
D08.811.277.352.640.700.700.500
D08.811.520.650.800
Unique ID
D043265
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D043265
Annotation
note X refs: TYPE C PHOSPHOLIPASES is also available
Scope Note
A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction.
Entry Term(s)
1-Phosphatidylinositol Phosphodiesterase
Monophosphatidylinositol Phosphodiesterase
Registry Number
EC 4.6.1.13
Previous Indexing
Phosphatidylinositols (1977-1982)
Phospholipase C (1998-2003)
Phosphoric Diester Hydrolases (1976-1997)
Public MeSH Note
2004; 1-PHOSPHATYDYLINOSITOL-GLYCAN-SPECIFIC PHOSPHOLIPASE C (now PHOSPHATIDYLINOSITOL DIACYLGLYCEROL-LYASE) was indexed under PHOSPHOLIPASE C 1998-2003; under PHOSPHORIC DIESTER HYDROLASES 1976-1997 & under PHOSPHATIDYLINOSITOLS 1977-1982
History Note
2004; use PHOSPHOTIDYLINOSITOL DIACYLGLYCEROL-LYASE (NM) 1980-2003
Date Established
2004/01/01
Date of Entry
2003/07/09
Revision Date
2007/07/11
Phosphatidylinositol Diacylglycerol-Lyase Preferred
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