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Receptors, Serotonin, 5-HT4 MeSH Descriptor Data 2022


MeSH Heading
Receptors, Serotonin, 5-HT4
Tree Number(s)
D12.776.543.750.670.800.400
D12.776.543.750.695.800.400
D12.776.543.750.720.850.400
Unique ID
D044422
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D044422
Scope Note
A subtype of G-protein-coupled SEROTONIN receptors that preferentially couple to GS STIMULATORY G-PROTEINS resulting in increased intracellular CYCLIC AMP. Several isoforms of the receptor exist due to ALTERNATIVE SPLICING of its mRNA.
Entry Version
RECEPT SEROTONIN 5 HT4
Entry Term(s)
5-HT4 Receptor
5-HT4L Receptor
5-HT4S Receptor
5-Hydroxytryptamine-4 Receptor
Receptor, Serotonin 4
Receptors, Serotonin, 5-HT4L
Receptors, Serotonin, 5-HT4S
Serotonin 4 Receptor
Serotonin 4 Receptors
Registry Number
158165-40-3
Previous Indexing
Receptors, Serotonin (1995-2003)
Public MeSH Note
2004; SEROTONIN 4 RECEPTOR (now RECEPTORS, SEROTININ, 5HT4) was indexed under RECEPTORS, SEROTONIN 1995-2003
History Note
2004; use RECEPTORS, SEROTININ, 5HT4 (NM) 1995-2003
Entry Combination
agonists:Serotonin 5-HT4 Receptor Agonists
antagonists & inhibitors:Serotonin 5-HT4 Receptor Antagonists
Date Established
2004/01/01
Date of Entry
2003/07/09
Revision Date
2016/06/17
Receptors, Serotonin, 5-HT4 Preferred
Receptors, Serotonin, 5-HT4S Narrower
Receptors, Serotonin, 5-HT4L Narrower
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