MeSH Browser

MeSH Heading: Receptor, PAR-1
Tree Number(s): D09.400.430.890.625.800.790; D12.776.395.550.625.800.790; D12.776.543.550.625.800.790; D12.776.543.750.695.875.500; D12.776.543.750.705.675.892.790; D12.776.543.750.750.850.399; D12.776.543.750.792.500.500
Unique ID: D044463
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D044463
Scope Note: A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms including decreased intracellular CYCLIC AMP, increased TYPE C PHOSPHOLIPASES and increased PHOSPHOLIPASE A2.
Entry Term(s): PAR-1 Receptor; PAR1 Receptor; Protease-Activated Receptor 1; Proteinase-Activated Receptor 1
Previous Indexing: Receptors, Thrombin (1997-2003)
Public MeSH Note: 2004; PROTEASE-ACTIVATED RECEPTOR-1 (now RECEPTOR, PROTIENASE-ACTIVATED) was indexed under RECEPTORS, THROMBIN 1997-2003
History Note: 2004; use RECEPTOR, PROTEINASE-ACTIVATED 1 (NM) 1997-2003
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M0283418
Scope Note: A thrombin receptor subtype that couples to HETEROTRIMERIC GTP-BINDING PROTEINS resulting in the activation of a variety of signaling mechanisms including decreased intracellular CYCLIC AMP, increased TYPE C PHOSPHOLIPASES and increased PHOSPHOLIPASE A2.
Terms: Receptor, PAR-1 Preferred Term
Term UI T313422
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); PAR-1 Receptor
Term UI T313419
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); PAR1 Receptor
Term UI T313420
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2004); Proteinase-Activated Receptor 1
Term UI T313421
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004); Protease-Activated Receptor 1
Term UI T313423
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2004)

Receptor, PAR-1 MeSH Descriptor Data 2024