Protease La MeSH Descriptor Data 2024

MeSH Heading: Protease La
Tree Number(s): D08.811.277.040.013.500.032.099.750; D08.811.277.040.025.024.032.099.750; D08.811.277.656.149.099.750; D08.811.277.656.300.065.750; D12.776.157.025.750.032.099.750
Unique ID: D049070
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D049070
Scope Note: A prokaryotic ATP-dependent protease that plays a role in the degradation of many abnormal proteins. It is a tetramer of 87-kDa subunits, each of which contains a proteolytic site and a ATP-binding site.
Entry Term(s): Endopeptidase La; Lon Protease
Registry Number: EC 3.4.21.53
Related Numbers: EC 3.4.21.53
Previous Indexing: Heat-Shock Proteins (1989-2004); Peptide Peptidohydrolases (1981-1988); Serine Endopeptidases (1989-2004)
Public MeSH Note: 2005; PROTEASE LA was indexed under SERINE ENDOPEPTIDASES and HEAT-SHOCK PROTEINS 1989-2004 & under PEPTIDE PEPTIDOHYDROLASES 1981-1988
History Note: 2005(1981)
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Acid Anhydride Hydrolases [D08.811.277.040]
      - AAA Proteins [D08.811.277.040.013]
        
        ATPases Associated with Diverse Cellular Activities [D08.811.277.040.013.500]
        
        ATP-Dependent Proteases [D08.811.277.040.013.500.032]
        
        ATP-Dependent Endopeptidases [D08.811.277.040.013.500.032.099]
        
        Endopeptidase Clp [D08.811.277.040.013.500.032.099.500]
        
        Protease La [D08.811.277.040.013.500.032.099.750]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Acid Anhydride Hydrolases [D08.811.277.040]
      - Adenosine Triphosphatases [D08.811.277.040.025]
        
        ATPases Associated with Diverse Cellular Activities [D08.811.277.040.025.024]
        
        ATP-Dependent Proteases [D08.811.277.040.025.024.032]
        
        ATP-Dependent Endopeptidases [D08.811.277.040.025.024.032.099]
        
        Endopeptidase Clp [D08.811.277.040.025.024.032.099.500]
        
        Protease La [D08.811.277.040.025.024.032.099.750]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - ATP-Dependent Proteases [D08.811.277.656.149]
        
        ATP-Dependent Endopeptidases [D08.811.277.656.149.099]
        
        Endopeptidase Clp [D08.811.277.656.149.099.500]
        
        Protease La [D08.811.277.656.149.099.750]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        ATP-Dependent Endopeptidases [D08.811.277.656.300.065]
        
        Endopeptidase Clp [D08.811.277.656.300.065.500]
        
        Protease La [D08.811.277.656.300.065.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - AAA Proteins [D12.776.157.025]
      - ATPases Associated with Diverse Cellular Activities [D12.776.157.025.750]
        
        ATP-Dependent Proteases [D12.776.157.025.750.032]
        
        ATP-Dependent Endopeptidases [D12.776.157.025.750.032.099]
        
        Endopeptidase Clp [D12.776.157.025.750.032.099.500]
        
        Protease La [D12.776.157.025.750.032.099.750]

Protease La Preferred

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