MeSH Browser

MeSH Heading: Large-Conductance Calcium-Activated Potassium Channels
Tree Number(s): D12.776.157.530.400.600.150.500; D12.776.543.550.450.750.150.500; D12.776.543.585.400.750.150.500
Unique ID: D051036
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051036
Scope Note: A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.
Entry Term(s): BK Channel; BK Channels; Big K Channel; Big K Channels; Large-Conductance Calcium-Activated Potassium Channel; Maxi K Channel; Maxi-K Channel; Maxi-K Channels; MaxiK Channel; MaxiK Channels
Public MeSH Note: 2006; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS was indexed under MEMBRANE PROTEINS 1993-1995, under POTASSIUM CHANNELS 1995-2002, & under POTASSIUM CHANNELS, CALCIUM-ACTIVATED 2002-2005
History Note: 2006(2993)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Carrier Proteins [D12.776.157]
    - Membrane Transport Proteins [D12.776.157.530]
      - Ion Channels [D12.776.157.530.400]
        
        Potassium Channels [D12.776.157.530.400.600]
        
        Potassium Channels, Calcium-Activated [D12.776.157.530.400.600.150]
        
        Intermediate-Conductance Calcium-Activated Potassium Channels [D12.776.157.530.400.600.150.249]
        
        Large-Conductance Calcium-Activated Potassium Channels [D12.776.157.530.400.600.150.500]
        
        Large-Conductance Calcium-Activated Potassium Channel alpha Subunits [D12.776.157.530.400.600.150.500.500]
        
        Large-Conductance Calcium-Activated Potassium Channel beta Subunits [D12.776.157.530.400.600.150.500.750]
        
        Small-Conductance Calcium-Activated Potassium Channels [D12.776.157.530.400.600.150.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Ion Channels [D12.776.543.550.450]
        
        Potassium Channels [D12.776.543.550.450.750]
        
        Potassium Channels, Calcium-Activated [D12.776.543.550.450.750.150]
        
        Intermediate-Conductance Calcium-Activated Potassium Channels [D12.776.543.550.450.750.150.249]
        
        Large-Conductance Calcium-Activated Potassium Channels [D12.776.543.550.450.750.150.500]
        
        Large-Conductance Calcium-Activated Potassium Channel alpha Subunits [D12.776.543.550.450.750.150.500.500]
        
        Large-Conductance Calcium-Activated Potassium Channel beta Subunits [D12.776.543.550.450.750.150.500.750]
        
        Small-Conductance Calcium-Activated Potassium Channels [D12.776.543.550.450.750.150.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Transport Proteins [D12.776.543.585]
      - Ion Channels [D12.776.543.585.400]
        
        Potassium Channels [D12.776.543.585.400.750]
        
        Potassium Channels, Calcium-Activated [D12.776.543.585.400.750.150]
        
        Intermediate-Conductance Calcium-Activated Potassium Channels [D12.776.543.585.400.750.150.249]
        
        Large-Conductance Calcium-Activated Potassium Channels [D12.776.543.585.400.750.150.500]
        
        Large-Conductance Calcium-Activated Potassium Channel alpha Subunits [D12.776.543.585.400.750.150.500.249]
        
        Large-Conductance Calcium-Activated Potassium Channel beta Subunits [D12.776.543.585.400.750.150.500.500]
        
        Small-Conductance Calcium-Activated Potassium Channels [D12.776.543.585.400.750.150.750]

Large-Conductance Calcium-Activated Potassium Channels Preferred

Concept UI: M0218785
Scope Note: A major class of calcium activated potassium channels whose members are voltage-dependent. MaxiK channels are activated by either membrane depolarization or an increase in intracellular Ca(2+). They are key regulators of calcium and electrical signaling in a variety of tissues.
Terms: Large-Conductance Calcium-Activated Potassium Channels Preferred Term
Term UI T627108
Date01/07/2005
LexicalTag NON
ThesaurusID NLM (2006); Large-Conductance Calcium-Activated Potassium Channel
Term UI T000998304
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); MaxiK Channels
Term UI T627109
Date01/07/2005
LexicalTag ABX
ThesaurusID NLM (2006); Big K Channels
Term UI T627110
Date01/07/2005
LexicalTag ABX
ThesaurusID NLM (2006); BK Channels
Term UI T627111
Date01/07/2005
LexicalTag ABX
ThesaurusID NLM (2006); Maxi-K Channels
Term UI T627112
Date01/07/2005
LexicalTag ABX
ThesaurusID NLM (2006); BK Channel
Term UI T000998305
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Big K Channel
Term UI T000998307
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Maxi-K Channel
Term UI T000998308
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); Maxi K Channel
Term UI T000998302
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021); MaxiK Channel
Term UI T000998310
Date11/20/2019
LexicalTag NON
ThesaurusID NLM (2021)

Large-Conductance Calcium-Activated Potassium Channels MeSH Descriptor Data 2024