MeSH Browser

MeSH Heading: Aquaporin 2
Tree Number(s): D12.776.157.530.400.500.040.437; D12.776.543.550.450.730.040.437; D12.776.543.585.400.730.040.530
Unique ID: D051399
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051399
Scope Note: Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.
Entry Term(s): AQP2 Protein; Aquaporin-2; Aquaporin-CD; Water Channel Of Collecting Duct
See Also: Diabetes Insipidus, Nephrogenic
Public MeSH Note: 2006; AQUAPORIN 2 was indexed under AQUAPORINS 1999-2005, & under ION CHANNELS 1995-1998, & under MEMBRANE PROTEINS 1993-1994
History Note: 2006(1993)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/07/01

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0213077
Scope Note: Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA MEMBRANE is regulated by VASOPRESSIN, and MUTATIONS in AQP2 have been implicated in a variety of kidney disorders including DIABETES INSIPIDUS.
Terms: Aquaporin 2 Preferred Term
Term UI T243076
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Aquaporin-2
Term UI T243077
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Aquaporin-CD
Term UI T243079
Date01/01/1955
LexicalTag ACX
ThesaurusID NLM (2006); Water Channel Of Collecting Duct
Term UI T243082
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); AQP2 Protein
Term UI T575568
Date03/04/2004
LexicalTag ABX
ThesaurusID NLM (2006)

Aquaporin 2 MeSH Descriptor Data 2024