MeSH Browser

MeSH Heading: Endocrine Disruptors
Tree Number(s): D27.505.696.353; D27.888.141
Unique ID: D052244
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D052244
Annotation: note entry term ENDOCRINE DISRUPTOR EFFECT: use only for the endocrine disruptor effect of a chemical substance
Scope Note: Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
Entry Term(s): Endocrine Disrupting Chemical; Endocrine Disrupting Chemicals; Endocrine Disruptor; Endocrine Disruptor Effect; Endocrine Disruptor Effects
Registry Numbers: 0
Previous Indexing: Endocrine Glands/drug effects (1993-2005); Endocrine System/drug effects (1997-2005)
See Also: Hormones, Hormone Substitutes, and Hormone Antagonists
Public MeSH Note: 2006
History Note: 2006
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Concept UI: M0483842
Registry Numbers: 0
Scope Note: Exogenous agents, synthetic and naturally occurring, which are capable of disrupting the functions of the ENDOCRINE SYSTEM including the maintenance of HOMEOSTASIS and the regulation of developmental processes. Endocrine disruptors are compounds that can mimic HORMONES, or enhance or block the binding of hormones to their receptors, or otherwise lead to activating or inhibiting the endocrine signaling pathways and hormone metabolism.
Terms: Endocrine Disruptors Preferred Term
Term UI T637962
Date04/26/2005
LexicalTag NON
ThesaurusID NLM (2006); Endocrine Disruptor
Term UI T000999039
Date11/21/2019
LexicalTag NON
ThesaurusID NLM (2021); Endocrine Disrupting Chemical
Term UI T000999040
Date11/21/2019
LexicalTag NON
ThesaurusID NLM (2021); Endocrine Disrupting Chemicals
Term UI T637961
Date04/26/2005
LexicalTag NON
ThesaurusID NLM (2006)

Endocrine Disruptors MeSH Descriptor Data 2025