Keratin-4 MeSH Descriptor Data 2024

MeSH Heading: Keratin-4
Tree Number(s): D05.750.078.593.450.600.400; D12.776.220.475.450.600.400; D12.776.860.607.650.400
Unique ID: D053527
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D053527
Scope Note: A type II keratin that is found associated with the KERATIN-13 in the internal stratified EPITHELIUM. Defects in gene for keratin-4 are a cause of HEREDITARY MUCOSAL LEUKOKERATOSIS.
Entry Term(s): Cytokeratin 4; Cytokeratin-4
Previous Indexing: Keratins (1989-2006)
Public MeSH Note: 2007; for CYTOKERATIN-4 see KERATIN 1989-2006
History Note: 2007(1989)
Entry Combination: deficiency:Leukokeratosis, Hereditary Mucosal
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 1955/01/01

Entry Combination: deficiency:Leukokeratosis, Hereditary Mucosal
Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Macromolecular Substances [D05]
- Polymers [D05.750]
  - Biopolymers [D05.750.078]
    - Intermediate Filament Proteins [D05.750.078.593]
      - Keratins [D05.750.078.593.450]
        
        Keratins, Type II [D05.750.078.593.450.600]
        
        Keratin-1 [D05.750.078.593.450.600.100]
        
        Keratin-2 [D05.750.078.593.450.600.200]
        
        Keratin-3 [D05.750.078.593.450.600.300]
        
        Keratin-4 [D05.750.078.593.450.600.400]
        
        Keratin-5 [D05.750.078.593.450.600.500]
        
        Keratin-6 [D05.750.078.593.450.600.600]
        
        Keratin-7 [D05.750.078.593.450.600.700]
        
        Keratin-8 [D05.750.078.593.450.600.800]
        
        Keratin-9 [D05.750.078.593.450.600.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Cytoskeletal Proteins [D12.776.220]
    - Intermediate Filament Proteins [D12.776.220.475]
      - Keratins [D12.776.220.475.450]
        
        Keratins, Type II [D12.776.220.475.450.600]
        
        Keratin-1 [D12.776.220.475.450.600.100]
        
        Keratin-2 [D12.776.220.475.450.600.200]
        
        Keratin-3 [D12.776.220.475.450.600.300]
        
        Keratin-4 [D12.776.220.475.450.600.400]
        
        Keratin-5 [D12.776.220.475.450.600.500]
        
        Keratin-6 [D12.776.220.475.450.600.600]
        
        Keratin-7 [D12.776.220.475.450.600.700]
        
        Keratin-8 [D12.776.220.475.450.600.800]
        
        Keratin-9 [D12.776.220.475.450.600.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Scleroproteins [D12.776.860]
    - Keratins [D12.776.860.607]
      - Keratins, Type II [D12.776.860.607.650]
        
        Keratin-1 [D12.776.860.607.650.100]
        
        Keratin-2 [D12.776.860.607.650.200]
        
        Keratin-3 [D12.776.860.607.650.300]
        
        Keratin-4 [D12.776.860.607.650.400]
        
        Keratin-5 [D12.776.860.607.650.500]
        
        Keratin-6 [D12.776.860.607.650.600]
        
        Keratin-7 [D12.776.860.607.650.700]
        
        Keratin-8 [D12.776.860.607.650.800]
        
        Keratin-9 [D12.776.860.607.650.900]

Keratin-4 Preferred

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