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An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.
Entry Version
IL 1ALPHA
Entry Term(s)
Hematopoietin-1
IL-1 alpha
Interleukin-1 alpha
Registry Numbers
0
Previous Indexing
Interleukin-1 (1988-2006)
Public MeSH Note
2007; see INTERLEUKIN-1 1988-2006; for HEMATOPOIETIN-1 see HEMATOPOIETIC CELL GROWTH FACTORS 1990-2006
An interleukin-1 subtype that occurs as a membrane-bound pro-protein form that is cleaved by proteases to form a secreted mature form. Unlike INTERLEUKIN-1BETA both membrane-bound and secreted forms of interleukin-1alpha are biologically active.