MeSH Browser

MeSH Heading: Receptors, KIR
Tree Number(s): D12.776.543.750.705.895.500
Unique ID: D054340
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054340
Annotation: general; prefer specifics
Scope Note: A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells.
Entry Term(s): KIR Family Receptors; KIR Receptor; KIR Receptors; Killer Cell Immunoglobulin-Like Receptor; Killer Cell Immunoglobulin-Like Receptors; Killer Immunoglobulin-Like Receptor; Killer Immunoglobulin-Like Receptor (KIR) Family of Receptors; Killer Inhibitory Receptor; Killer Inhibitory Receptors; Receptor, Killer Inhibitory; Receptor, p58 NK Cell; p58 NK Cell Inhibitory Receptor; p58 NK Cell Receptor; p58 NK Cell Receptors; p58 Natural Killer Cell Receptor
Public MeSH Note: 2008; KIR RECEPTORS (now RECEPTORS, KIR) was indexed under RECEPTORS, IMMUNOLOGIC 1997-2007
History Note: 2008(1997)
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2008/07/08

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Natural Killer Cell [D12.776.543.750.705.895]
        
        Receptors, KIR [D12.776.543.750.705.895.500]
        
        Receptors, KIR2DL1 [D12.776.543.750.705.895.500.249]
        
        Receptors, KIR2DL2 [D12.776.543.750.705.895.500.374]
        
        Receptors, KIR2DL3 [D12.776.543.750.705.895.500.437]
        
        Receptors, KIR2DL4 [D12.776.543.750.705.895.500.468]
        
        Receptors, KIR2DL5 [D12.776.543.750.705.895.500.484]
        
        Receptors, KIR3DL1 [D12.776.543.750.705.895.500.500]
        
        Receptors, KIR3DL2 [D12.776.543.750.705.895.500.750]
        
        Receptors, KIR3DS1 [D12.776.543.750.705.895.500.890]
        
        Receptors, Natural Cytotoxicity Triggering [D12.776.543.750.705.895.750]
        
        Receptors, NK Cell Lectin-Like [D12.776.543.750.705.895.800]

Receptors, KIR Preferred

Concept UI: M0281250
Scope Note: A family of receptors found on NK CELLS that have specificity for a variety of HLA ANTIGENS. KIR receptors contain up to three different extracellular immunoglobulin-like domains referred to as D0, D1, and D2 and play an important role in blocking NK cell activation against cells expressing the appropriate HLA antigens thus preventing cell lysis. Although they are often referred to as being inhibitory receptors, a subset of KIR receptors may also play an activating role in NK cells.
Terms: Receptors, KIR Preferred Term
Term UI T686713
Date11/27/2006
LexicalTag ABX
ThesaurusID NLM (2008); p58 NK Cell Receptors
Term UI T276913
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); Receptor, p58 NK Cell
Term UI T276914
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); p58 Natural Killer Cell Receptor
Term UI T276915
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); KIR Receptor
Term UI T311247
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); p58 NK Cell Inhibitory Receptor
Term UI T311253
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); Receptor, Killer Inhibitory
Term UI T311254
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008); Killer Inhibitory Receptor
Term UI T311255
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008); Killer Immunoglobulin-Like Receptor
Term UI T534580
Date03/05/2003
LexicalTag NON
ThesaurusID NLM (2008); Killer Cell Immunoglobulin-Like Receptor
Term UI T685101
Date10/27/2006
LexicalTag NON
ThesaurusID NLM (2008); KIR Family Receptors
Term UI T686694
Date11/27/2006
LexicalTag ABX
ThesaurusID NLM (2008); KIR Receptors
Term UI T686695
Date11/27/2006
LexicalTag ABX
ThesaurusID NLM (2008); Killer Immunoglobulin-Like Receptor (KIR) Family of Receptors
Term UI T686696
Date11/27/2006
LexicalTag ABX
ThesaurusID NLM (2008); Killer Cell Immunoglobulin-Like Receptors
Term UI T686697
Date11/27/2006
LexicalTag NON
ThesaurusID NLM (2008); p58 NK Cell Receptor
Term UI T276912
Date01/01/1955
LexicalTag ABX
ThesaurusID NLM (2008); Killer Inhibitory Receptors
Term UI T686943
Date11/30/2006
LexicalTag NON
ThesaurusID NLM (2008)

Receptors, KIR MeSH Descriptor Data 2024