- Concept UI
- M0133732
- Registry Numbers
- 126465-35-8
- Scope Note
- A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.
- Terms
-
Perforin
Preferred Term
Term UI
T163737
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2008)
-
Perforin 1
Term UI
T163733
Date01/01/1955
LexicalTag
NON
ThesaurusID
NLM (2008)
-
Cytolysin
Term UI
T602609
Date08/10/2004
LexicalTag
NON
ThesaurusID
NLM (2008)
-
Lymphocyte Pore-Forming Protein
Term UI
T602608
Date08/10/2004
LexicalTag
NON
ThesaurusID
NLM (2008)