MeSH Browser

MeSH Heading: Group IV Phospholipases A2
Tree Number(s): D08.811.277.352.100.680.750.937.625.249
Unique ID: D054513
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054513
Annotation: /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
Scope Note: A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.
Entry Term(s): Cytosolic Phospholipase A2 alpha; Cytosolic Phospholipase A2 beta; Cytosolic Phospholipase A2 delta; Cytosolic Phospholipase A2 epsilon; Cytosolic Phospholipase A2 gamma; Group IV Cytosolic Phospholipase A2; Group IVA Phospholipase A2; Group IVA Phospholipases A2; Group IVB Phospholipase A2; Group IVB Phospholipases A2; Group IVC Phospholipase A2; Group IVC Phospholipases A2; Group IVD Phospholipase A2; Group IVD Phospholipases A2; Group IVE Phospholipase A2; Group IVE Phospholipases A2; Group IVF Phospholipase A2; Group IVF Phospholipases A2; PLA(2)-IV; PLA2-IV; Phospholipase A(2)alpha; Phospholipase A2 Group IVA; Phospholipase A2 IV; Phospholipase A2, Group IVB; Phospholipase A2, Group IVC; Phospholipase A2, Group IVD; Phospholipase A2, Group IVE; Phospholipase A2, Group IVF; Phospholipase A2-alpha; Phospholipase A2-beta; Phospholipase A2-gamma; Phospholipases A2, Group IV; cPLA2-alpha; cPLA2-gamma
Related Numbers: EC 3.1.1.4
Public MeSH Note: 2008; GROUP IV PHOSPHOLIPASE A2 was indexed under to PHOSPHOLIPASES A 1997-2007; PHOSPHOLIPASE A2-ALPHA was indexed under PHOSPHOLIPASES A 2000-2007; PHOSPHOLIPASE A2-BETA was indexed under PHOSPHOLIPASES A 1999-2007; PHOSPHOLIPASE A2-GAMMA was indexed under PHOSPHOLIPASES A 1998-2007
History Note: 2008(1997)
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2013/07/08

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Esterases [D08.811.277.352]
      - Carboxylic Ester Hydrolases [D08.811.277.352.100]
        
        Phospholipases [D08.811.277.352.100.680]
        
        Phospholipases A [D08.811.277.352.100.680.750]
        
        Phospholipases A2 [D08.811.277.352.100.680.750.937]
        
        Phospholipases A2, Cytosolic [D08.811.277.352.100.680.750.937.625]
        
        Group IV Phospholipases A2 [D08.811.277.352.100.680.750.937.625.249]
        
        Peroxiredoxin VI [D08.811.277.352.100.680.750.937.625.624]

Group IV Phospholipases A2 Preferred

Concept UI: M0222411
Related Numbers: EC 3.1.1.4
Scope Note: A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.
Terms: Group IV Phospholipases A2 Preferred Term
Term UI T689785
Date01/23/2007
LexicalTag NON
ThesaurusID NLM (2008); Group IV Cytosolic Phospholipase A2
Term UI T454997
Date07/21/2001
LexicalTag NON
ThesaurusID NLM (2008); Phospholipase A2 IV
Term UI T252416
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008); Phospholipases A2, Group IV
Term UI T690380
Date01/29/2007
LexicalTag NON
ThesaurusID NLM (2008); PLA(2)-IV
Term UI T252414
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (2008); PLA2-IV
Term UI T252415
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (2008)

Group IVA Phospholipase A2 Narrower

Concept UI: M0505797
Terms: Group IVA Phospholipase A2 Preferred Term
Term UI T689831
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); cPLA2-alpha
Term UI T407277
Date02/16/2000
LexicalTag NON
ThesaurusID NLM (2008); Cytosolic Phospholipase A2 alpha
Term UI T689826
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Group IVA Phospholipases A2
Term UI T689832
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Phospholipase A(2)alpha
Term UI T589695
Date06/07/2004
LexicalTag NON
ThesaurusID NLM (2008); Phospholipase A2 Group IVA
Term UI T689833
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Phospholipase A2-alpha
Term UI T407276
Date02/16/2000
LexicalTag NON
ThesaurusID NLM (2008)

Group IVB Phospholipase A2 Narrower

Concept UI: M0505798
Terms: Group IVB Phospholipase A2 Preferred Term
Term UI T689834
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Cytosolic Phospholipase A2 beta
Term UI T689836
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Group IVB Phospholipases A2
Term UI T689837
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Phospholipase A2, Group IVB
Term UI T689835
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Phospholipase A2-beta
Term UI T336383
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008)

Group IVC Phospholipase A2 Narrower

Concept UI: M0505799
Terms: Group IVC Phospholipase A2 Preferred Term
Term UI T689838
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Group IVC Phospholipases A2
Term UI T689840
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Phospholipase A2, Group IVC
Term UI T689841
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Phospholipase A2-gamma
Term UI T324738
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008); cPLA2-gamma
Term UI T324737
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2008); Cytosolic Phospholipase A2 gamma
Term UI T689839
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008)

Group IVD Phospholipase A2 Narrower

Concept UI: M0505801
Terms: Group IVD Phospholipase A2 Preferred Term
Term UI T689844
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Cytosolic Phospholipase A2 delta
Term UI T689845
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Group IVD Phospholipases A2
Term UI T689847
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Phospholipase A2, Group IVD
Term UI T689846
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008)

Group IVE Phospholipase A2 Narrower

Concept UI: M0505804
Terms: Group IVE Phospholipase A2 Preferred Term
Term UI T689852
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Cytosolic Phospholipase A2 epsilon
Term UI T689853
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Group IVE Phospholipases A2
Term UI T689854
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008); Phospholipase A2, Group IVE
Term UI T689855
Date01/24/2007
LexicalTag NON
ThesaurusID NLM (2008)

Group IVF Phospholipase A2 Narrower

Group IV Phospholipases A2 MeSH Descriptor Data 2024