MeSH Browser

MeSH Heading: Calcium-Calmodulin-Dependent Protein Kinase Type 2
Tree Number(s): D08.811.913.696.620.682.700.125.200; D12.776.476.563.125.200
Unique ID: D054732
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054732
Scope Note: A multifunctional calcium-calmodulin-dependent protein kinase subtype that occurs as an oligomeric protein comprised of twelve subunits. It differs from other enzyme subtypes in that it lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE.
Entry Term(s): Ca(2+)-Calmodulin Dependent Protein Kinase Type II; CaCMKII; CaM KII; CaM KIIalpha; CaM KIIbeta; CaM KIIdelta; CaM Kinase II; CaM Kinase II alpha; CaM Kinase II beta; CaM Kinase II delta; CaM Kinase II gamma; CaM PK II; CaM-Kinase II; CaM-Kinase IIalpha; CaMKII; CaMKIIgamma; Calcium-Calmodulin Dependent Protein Kinase II beta; Calcium-Calmodulin Dependent Protein Kinase II delta; Calcium-Calmodulin Dependent Protein Kinase II gamma; Calcium-Calmodulin Protein Kinase II; Calcium-Calmodulin-Dependent PK Type II; Calcium-Calmodulin-Dependent Protein Kinase Type 2 alpha Subunit; Calcium-Calmodulin-Dependent Protein Kinase Type 2 beta Subunit; Calcium-Calmodulin-Dependent Protein Kinase Type 2 delta Subunit; Calcium-Calmodulin-Dependent Protein Kinase Type 2 gamma Subunit; Calcium-Dependent CaM Kinase II; Calmodulin Kinase IIalpha; Calmodulin-Dependent Protein Kinase II
Registry Number: EC 2.7.11.17
Related Numbers: EC 2.7.11.17
Public MeSH Note: 2008; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2 was indexed under CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASES 1993-2006
History Note: 2008(1993)
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2021/05/20

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Phosphotransferases [D08.811.913.696]
      - Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
        
        Protein Kinases [D08.811.913.696.620.682]
        
        Protein Serine-Threonine Kinases [D08.811.913.696.620.682.700]
        
        Calcium-Calmodulin-Dependent Protein Kinases [D08.811.913.696.620.682.700.125]
        
        Calcium-Calmodulin-Dependent Protein Kinase Kinase [D08.811.913.696.620.682.700.125.049]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 1 [D08.811.913.696.620.682.700.125.100]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 2 [D08.811.913.696.620.682.700.125.200]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 4 [D08.811.913.696.620.682.700.125.350]
        
        Death-Associated Protein Kinases [D08.811.913.696.620.682.700.125.387]
        
        Elongation Factor 2 Kinase [D08.811.913.696.620.682.700.125.425]
        
        Myosin-Light-Chain Kinase [D08.811.913.696.620.682.700.125.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Protein Serine-Threonine Kinases [D12.776.476.563]
      - Calcium-Calmodulin-Dependent Protein Kinases [D12.776.476.563.125]
        
        Calcium-Calmodulin-Dependent Protein Kinase Kinase [D12.776.476.563.125.049]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 1 [D12.776.476.563.125.100]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 2 [D12.776.476.563.125.200]
        
        Calcium-Calmodulin-Dependent Protein Kinase Type 4 [D12.776.476.563.125.350]
        
        Death-Associated Protein Kinases [D12.776.476.563.125.387]
        
        Elongation Factor 2 Kinase [D12.776.476.563.125.425]
        
        Myosin-Light-Chain Kinase [D12.776.476.563.125.500]

Calcium-Calmodulin-Dependent Protein Kinase Type 2 Preferred

Concept UI: M0223941
Registry Number: EC 2.7.11.17
Related Numbers: EC 2.7.11.17
Scope Note: A multifunctional calcium-calmodulin-dependent protein kinase subtype that occurs as an oligomeric protein comprised of twelve subunits. It differs from other enzyme subtypes in that it lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE.
Terms: Calcium-Calmodulin-Dependent Protein Kinase Type 2 Preferred Term
Term UI T692626
Date03/01/2007
LexicalTag NON
ThesaurusID NLM (2008); CaM PK II
Term UI T253940
LexicalTag ABB
ThesaurusID NLM (2008); CaM Kinase II
Term UI T253941
LexicalTag ABX
ThesaurusID NLM (2008); CaM-Kinase II
Term UI T253942
LexicalTag ABX
ThesaurusID NLM (2008); Calcium-Dependent CaM Kinase II
Term UI T253945
LexicalTag NON
ThesaurusID NLM (2008); Calcium-Calmodulin-Dependent PK Type II
Term UI T365709
LexicalTag NON
ThesaurusID NLM (2008); CaMKII
Term UI T423185
Date09/02/2000
LexicalTag ABX
ThesaurusID NLM (2008); Ca(2+)-Calmodulin Dependent Protein Kinase Type II
Term UI T643827
Date06/21/2005
LexicalTag NON
ThesaurusID NLM (2008); CaCMKII
Term UI T691886
Date02/20/2007
LexicalTag ACR
ThesaurusID NLM (2008); Calcium-Calmodulin Protein Kinase II
Term UI T691887
Date02/20/2007
LexicalTag NON
ThesaurusID NLM (2008); CaM KII
Term UI T253939
LexicalTag ACR
ThesaurusID NLM (2008); Calmodulin-Dependent Protein Kinase II
Term UI T253946
LexicalTag NON
ThesaurusID NLM (2008)

Calcium-Calmodulin-Dependent Protein Kinase Type 2 delta Subunit Narrower

Calcium-Calmodulin-Dependent Protein Kinase Type 2 alpha Subunit Narrower

Concept UI: M0444327
Registry Number: EC 2.7.11.17
Terms: Calcium-Calmodulin-Dependent Protein Kinase Type 2 alpha Subunit Preferred Term
Term UI T692629
Date03/01/2007
LexicalTag NON
ThesaurusID NLM (2008); CaM KIIalpha
Term UI T529643
Date01/02/2003
LexicalTag ABX
ThesaurusID NLM (2008); Calmodulin Kinase IIalpha
Term UI T529642
Date01/02/2003
LexicalTag NON
ThesaurusID NLM (2008); CaM Kinase II alpha
Term UI T692630
Date03/01/2007
LexicalTag ABX
ThesaurusID NLM (2008); CaM-Kinase IIalpha
Term UI T253943
LexicalTag ABX
ThesaurusID NLM (2008)

Calcium-Calmodulin-Dependent Protein Kinase Type 2 beta Subunit Narrower

Calcium-Calmodulin-Dependent Protein Kinase Type 2 gamma Subunit Narrower

Calcium-Calmodulin-Dependent Protein Kinase Type 2 MeSH Descriptor Data 2024