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Inverted Repeat Sequences MeSH Descriptor Data 2025


MeSH Heading
Inverted Repeat Sequences
Tree Number(s)
G02.111.570.080.708.800.325
G05.360.080.708.800.325
Unique ID
D055029
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D055029
Scope Note
Copies of nucleic acid sequence that are arranged in opposing orientation. They may lie adjacent to each other (tandem) or be separated by some sequence that is not part of the repeat (hyphenated). They may be true palindromic repeats, i.e. read the same backwards as forward, or complementary which reads as the base complement in the opposite orientation. Complementary inverted repeats have the potential to form hairpin loop or stem-loop structures which results in cruciform structures (such as CRUCIFORM DNA) when the complementary inverted repeats occur in double stranded regions.
Entry Term(s)
Hairpin Loop Sequence
Inverted Repeat Sequence
Inverted Tandem Repeats
Palindromic Repeat Sequences
Sequence Palindromes
Stem-Loop Sequence
Public MeSH Note
2009; for INVERTED REPEAT SEQUENCE see REPETITIVE SEQUENCES, NUCLEIC ACID 1990-2008
History Note
2009; for INVERTED REPEAT SEQUENCE use REPETITIVE SEQUENCES, NUCLEIC ACID 1990-2008
Date Established
2009/01/01
Date of Entry
2008/07/08
Revision Date
2013/07/09
Inverted Repeat Sequences Preferred
Inverted Tandem Repeats Narrower
Hairpin Loop Sequence Narrower
Stem-Loop Sequence Narrower
Palindromic Repeat Sequences Narrower
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