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DNA, Satellite MeSH Descriptor Data 2022


MeSH Heading
DNA, Satellite
Tree Number(s)
D13.444.308.480
G02.111.570.080.708.800.150
G05.360.080.708.800.150
G05.360.340.024.220.150
G05.360.340.024.850.150
Unique ID
D004276
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D004276
Scope Note
Highly repetitive DNA sequences found in HETEROCHROMATIN, mainly near centromeres. They are composed of simple sequences (very short) (see MINISATELLITE REPEATS) repeated in tandem many times to form large blocks of sequence. Additionally, following the accumulation of mutations, these blocks of repeats have been repeated in tandem themselves. The degree of repetition is on the order of 1000 to 10 million at each locus. Loci are few, usually one or two per chromosome. They were called satellites since in density gradients, they often sediment as distinct, satellite bands separate from the bulk of genomic DNA owing to a distinct BASE COMPOSITION.
Entry Term(s)
Satellite DNA
Satellite I DNA
Registry Number
0
NLM Classification #
QU 58.5
Previous Indexing
DNA (1966-1974)
See Also
Centromere
Public MeSH Note
80; was see under DNA 1975-79
History Note
80(75); was see under DNA 1975-79
Date Established
1980/01/01
Date of Entry
1974/11/11
Revision Date
2008/07/08
DNA, Satellite Preferred
Satellite I DNA Narrower
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