MeSH Browser

MeSH Heading: DNA, Antisense
Tree Number(s): D13.150.200; D13.444.308.150; D13.444.600.150.200; D27.720.470.530.600.150.200
Unique ID: D016373
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016373
Scope Note: DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.
Entry Term(s): Anti-Sense DNA; Antisense DNA
Registry Numbers: 0
NLM Classification #: QU 58.5
Previous Indexing: DNA (1988-1990)
Public MeSH Note: 91
History Note: 91
Date Established: 1991/01/01
Date of Entry: 1990/05/25
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analogs & derivatives (AA)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0025051
Registry Numbers: 0
Scope Note: DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.
Terms: DNA, Antisense Preferred Term
Term UI T048932
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1991); Antisense DNA
Term UI T048931
Date04/24/1990
LexicalTag NON
ThesaurusID NLM (1991); Anti-Sense DNA
Term UI T048933
Date01/27/1993
LexicalTag NON
ThesaurusID NLM (1994)

DNA, Antisense MeSH Descriptor Data 2025