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Voltage-Gated Sodium Channel beta-1 Subunit MeSH Descriptor Data 2024


MeSH Heading
Voltage-Gated Sodium Channel beta-1 Subunit
Tree Number(s)
D12.776.157.530.400.875.750.960.100
D12.776.543.550.450.875.750.970.100
D12.776.543.585.400.875.750.970.100
D12.776.631.960.970.100
Unique ID
D062547
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D062547
Scope Note
A voltage-gated sodium channel beta subunit abundantly expressed in SKELETAL MUSCLE; HEART; and BRAIN. It non-covalently associates with voltage-gated alpha subunits. Defects in the SCN1B gene, which codes for this beta subunit, are associated with generalized epilepsy with febrile seizures plus, type 1, and Brugada syndrome 5.
Entry Term(s)
SCN1B Sodium Channel beta Subunit
Registry Number
0
Previous Indexing
Sodium Channels (2002-2012)
See Also
Brugada Syndrome
Public MeSH Note
2013
History Note
2013
Entry Combination
agonists:Voltage-Gated Sodium Channel Agonists
antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
Date Established
2013/01/01
Date of Entry
2012/07/03
Revision Date
2016/07/01
Voltage-Gated Sodium Channel beta-1 Subunit Preferred
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