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Cyclic GMP-Dependent Protein Kinase Type I MeSH Descriptor Data 2025


MeSH Heading
Cyclic GMP-Dependent Protein Kinase Type I
Tree Number(s)
D08.811.913.696.620.682.700.150.150.500
D12.776.476.563.150.150.500
Unique ID
D062965
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D062965
Scope Note
A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction. Two isoforms, PKGIalpha and PKGIbeta, of the type I protein kinase exist due to alternative splicing of its mRNA.
Entry Term(s)
PKGI beta
PKGIalpha
PKGIbeta
Protein Kinase G I alpha
cGK-Ialpha
cGMP-Dependent Protein Kinase I
cGMP-Dependent Protein Kinase Ialpha
cGMP-Dependent Protein Kinase Ibeta
Registry Numbers
EC 2.7.11.12
EC 2.7.11.12
EC 2.7.11.12
Related Numbers
EC 2.7.11.12
Public MeSH Note
2013; CGMP-DEPENDENT PROTEIN KINASE I (now CYCLIC GMP-DEPENDENT PROTEIN KINASE TYPE I) was indexed under CYCLIC GMP DEPENDENT PROTEIN KINASE TYPE I 1994-2012
History Note
2013
Date Established
2013/01/01
Date of Entry
2012/07/03
Revision Date
2021/05/21
Cyclic GMP-Dependent Protein Kinase Type I Preferred
cGMP-Dependent Protein Kinase Ialpha Narrower
cGMP-Dependent Protein Kinase Ibeta Narrower
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