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Spike Glycoprotein, Coronavirus MeSH Descriptor Data 2024

MeSH Heading
Spike Glycoprotein, Coronavirus
Tree Number(s)
Unique ID
RDF Unique Identifier
Scope Note
A class I viral fusion protein that forms the characteristic spikes, or peplomers, found on the viral surface that mediate virus attachment, fusion, and entry into the host cell. During virus maturation, it is cleaved into two subunits: S1, which binds to receptors in the host cell, and S2, which mediates membrane fusion.
Entry Term(s)
E2 Spike Glycoprotein, Coronavirus
Glycoprotein S, Coronavirus
Spike Glycoprotein S1, Coronavirus
Spike Glycoprotein, Bovine Coronavirus
Spike Glycoproteins, Coronavirus
Spike Protein S2, Coronavirus
Spike Protein, Coronavirus
Registry Number
Previous Indexing
Membrane Glycoproteins (1991-2013)
Viral Envelope Proteins (1983-2013)
Viral Proteins (1979-1982)
Public MeSH Note
2014; was indexed under MEMBRANE GLYCOPROTEINS 1991-2013 and VIRAL ENVELOPE PROTEINS 1991-2013
History Note
Date Established
Date of Entry
Revision Date
Spike Glycoprotein, Coronavirus Preferred
Spike Glycoprotein S1, Coronavirus Narrower
Spike Glycoprotein, Bovine Coronavirus Narrower
Spike Protein S2, Coronavirus Narrower
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