MeSH Browser

MeSH Heading: Adenylosuccinate Synthase
Tree Number(s): D08.811.464.259.100
Unique ID: D000265
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000265
Scope Note: A carbon-nitrogen ligase. During purine ribonucleotide biosynthesis, this enzyme catalyzes the synthesis of adenylosuccinate from GTP; IMP; and aspartate with the formation of orthophosphate and GDP. EC 6.3.4.4.
Entry Term(s): Adenylosuccinate Synthetase; Succino-AMP Synthetase
Related Numbers: 9023-57-8
CAS Type 1 Name: IMP:L-aspartate ligase (GDP-forming)
Previous Indexing: Aspartic Acid (1966-1978); Inosine Monophosphate (1975-1978); Inosine Nucleotides (1971-1978); Ligases (1966-1978)
Public MeSH Note: 98; see ADENYLOSUCCINATE SYNTHETASE 1991-97; see LIGASES 1979-90
History Note: 98(79)
Date Established: 1991/01/01
Date of Entry: 1978/05/16
Revision Date: 2003/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Adenylosuccinate Synthase MeSH Descriptor Data 2024