NLM Logo

Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted.

The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov.

Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

Cellular Senescence MeSH Descriptor Data 2025


MeSH Heading
Cellular Senescence
Tree Number(s)
G04.043
G07.345.124.130
Unique ID
D016922
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D016922
Annotation
not for micro-organisms
Scope Note
Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
Entry Term(s)
Aging, Cell
Cell Ageing
Cell Aging
Cell Senescence
Cellular Ageing
Cellular Aging
Replicative Senescence
Senescence, Cellular
Senescence, Replicative
Previous Indexing
Cell Survival (1977-1991)
Erythrocyte Aging (1967-1991)
See Also
Cell Death
Plant Senescence
Public MeSH Note
2018; see CELL AGING 1992-2017; see CELL SURVIVAL 1977-1991; for CELL SENESCENCE and SENESCENCE, CELLULAR see CELL SURVIVAL 1991
History Note
2018 (1992); use CELL SURVIVAL 1977-1991
Date Established
1992/01/01
Date of Entry
1991/05/30
Revision Date
2021/07/07
Cellular Senescence Preferred
Cell Aging Narrower
page delivered in 0.145s