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Cyclic GMP MeSH Descriptor Data 2025


MeSH Heading
Cyclic GMP
Tree Number(s)
D03.633.100.759.646.454.160
D13.695.462.275
D13.695.667.454.160
D13.695.827.426.160
Unique ID
D006152
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D006152
Scope Note
Guanosine cyclic 3',5'-(hydrogen phosphate). A guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions. It is a cellular regulatory agent and has been described as a second messenger. Its levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed)
Entry Version
CYCL GMP
Entry Term(s)
Guanosine Cyclic 3',5'-Monophosphate
Guanosine Cyclic 3,5 Monophosphate
Guanosine Cyclic Monophosphate
Guanosine Cyclic-3',5'-Monophosphate
Registry Numbers
H2D2X058MU
Related Numbers
7665-99-8
CAS Type 1 Name
Guanosine, cyclic 3',5'-(hydrogen phosphate)
NLM Classification #
QU 57
Previous Indexing
Guanine Nucleotides (1966-1971)
Public MeSH Note
94; was GUANOSINE CYCLIC MONOPHOSPHATE 1980-93, was GUANOSINE CYCLIC-3',5'-MONOPHOSPHATE 1978-79, was GUANOSINE CYCLIC 3',5' MONOPHOSPHATE 1972-77; CYCLIC GMP was see GUANOSINE CYCLIC MONOPHOSPHATE 1975-93; GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE was see GUANOSINE CYCLIC MONOPHOSPHATE 1980-93
Online Note
use CYCLIC GMP to search GUANOSINE CYCLIC MONOPHOSPHATE & GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE 1980-93 & GUANOSINE CYCLIC-3',5'-MONOPHOSPHATE 1971-79 (as Prov 1971)
History Note
94; was GUANOSINE CYCLIC MONOPHOSPHATE 1980-93, was GUANOSINE CYCLIC-3',5'-MONOPHOSPHATE 1978-79, was GUANOSINE CYCLIC 3',5' MONOPHOSPHATE 1971-77 (Prov 1971); CYCLIC GMP was see GUANOSINE CYCLIC MONOPHOSPHATE 1975-93; GUANOSINE CYCLIC 2',3'-MONOPHOSPHATE was see GUANOSINE CYCLIC MONOPHOSPHATE 1980-93
Date Established
1972/01/01
Date of Entry
1999/01/01
Revision Date
2016/05/28
Cyclic GMP Preferred
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