MeSH Browser

MeSH Heading: fas Receptor
Tree Number(s): D12.776.543.750.690.500; D12.776.543.750.705.852.760.195
Unique ID: D019014
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019014
Scope Note: A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.
Entry Version: FAS RECEPT
Entry Term(s): APO-1 Antigen; Antigens, CD95; CD95 Antigen; CD95 Antigens; Fas Cell Surface Death Receptor; Receptors, fas; TNFRSF6 Receptor; Tumor Necrosis Factor Receptor Superfamily, Member 6; fas Antigen; fas Antigens; fas Receptors
Previous Indexing: Antigens, Surface (1989-1995)
See Also: Autoimmune Lymphoproliferative Syndrome
Public MeSH Note: 2018; see ANTIGENS, CD95 1989-2017; FAS ANTIGEN was indexed under ANTIGENS, SURFACE 1989-1995; FAS RECEPTOR was indexed under RECEPTORS, TUMOR NECROSIS FACTOR 1998-1999
History Note: 2018 (1989)
Date Established: 1996/01/01
Date of Entry: 1995/05/26
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Death Domain [D12.776.543.750.690]
        
        fas Receptor [D12.776.543.750.690.500]
        
        Edar Receptor [D12.776.543.750.690.550]
        
        Receptors, TNF-Related Apoptosis-Inducing Ligand [D12.776.543.750.690.600]
        
        Receptors, Tumor Necrosis Factor, Member 25 [D12.776.543.750.690.725]
        
        Receptors, Tumor Necrosis Factor, Type I [D12.776.543.750.690.750]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]
      - Receptors, Immunologic [D12.776.543.750.705]
        
        Receptors, Cytokine [D12.776.543.750.705.852]
        
        Receptors, Tumor Necrosis Factor [D12.776.543.750.705.852.760]
        
        Tumor Necrosis Factor Receptor Superfamily, Member 7 [D12.776.543.750.705.852.760.048]
        
        Ki-1 Antigen [D12.776.543.750.705.852.760.072]
        
        CD40 Antigens [D12.776.543.750.705.852.760.097]
        
        fas Receptor [D12.776.543.750.705.852.760.195]
        
        Tumor Necrosis Factor Receptor Superfamily, Member 9 [D12.776.543.750.705.852.760.220]
        
        B-Cell Activation Factor Receptor [D12.776.543.750.705.852.760.222]
        
        B-Cell Maturation Antigen [D12.776.543.750.705.852.760.226]
        
        Etanercept [D12.776.543.750.705.852.760.232]
        
        Glucocorticoid-Induced TNFR-Related Protein [D12.776.543.750.705.852.760.238]
        
        Lymphotoxin beta Receptor [D12.776.543.750.705.852.760.245]
        
        Receptor Activator of Nuclear Factor-kappa B [D12.776.543.750.705.852.760.345]
        
        Receptors, Ectodysplasin [D12.776.543.750.705.852.760.347]
        
        Receptors, OX40 [D12.776.543.750.705.852.760.350]
        
        Receptors, TNF-Related Apoptosis-Inducing Ligand [D12.776.543.750.705.852.760.396]
        
        Receptors, Tumor Necrosis Factor, Member 14 [D12.776.543.750.705.852.760.500]
        
        Receptors, Tumor Necrosis Factor, Member 25 [D12.776.543.750.705.852.760.505]
        
        Receptors, Tumor Necrosis Factor, Type I [D12.776.543.750.705.852.760.597]
        
        Receptors, Tumor Necrosis Factor, Type II [D12.776.543.750.705.852.760.798]
        
        Transmembrane Activator and CAML Interactor Protein [D12.776.543.750.705.852.760.899]
        
        Tumor Necrosis Factor Decoy Receptors [D12.776.543.750.705.852.760.949]
        
        TWEAK Receptor [D12.776.543.750.705.852.760.974]

fas Receptor Preferred

Concept UI: M0028392
Scope Note: A tumor necrosis factor receptor subtype found in a variety of tissues and on activated LYMPHOCYTES. It has specificity for FAS LIGAND and plays a role in regulation of peripheral immune responses and APOPTOSIS. Multiple isoforms of the protein exist due to multiple ALTERNATIVE SPLICING. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM. Mutations in the CD95 gene are associated with cases of autoimmune lymphoproliferative syndrome.
Terms: fas Receptor Preferred Term
Term UI T325044
Date11/04/1999
LexicalTag NON
ThesaurusID NLM (2000); fas Antigen
Term UI T056737
Date01/06/1995
LexicalTag NON
ThesaurusID NLM (1996); fas Antigens
Term UI T056738
Date01/06/1995
LexicalTag NON
ThesaurusID NLM (1996); APO-1 Antigen
Term UI T056739
Date01/06/1995
LexicalTag NON
ThesaurusID NLM (1996); CD95 Antigen
Term UI T056740
Date01/06/1995
LexicalTag NON
ThesaurusID NLM (1996); CD95 Antigens
Term UI T056741
Date01/06/1995
LexicalTag NON
ThesaurusID NLM (1996); Antigens, CD95
Term UI T056742
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1996); Receptors, fas
Term UI T325043
Date11/04/1999
LexicalTag NON
ThesaurusID NLM (2000); fas Receptors
Term UI T363745
Date11/04/1999
LexicalTag NON
ThesaurusID NLM (2000); Tumor Necrosis Factor Receptor Superfamily, Member 6
Term UI T572160
Date02/10/2004
LexicalTag NON
ThesaurusID NLM (2005); Fas Cell Surface Death Receptor
Term UI T000888283
Date10/20/2015
LexicalTag NON
ThesaurusID NLM (2017); TNFRSF6 Receptor
Term UI T572161
Date02/10/2004
LexicalTag ACX
ThesaurusID NLM (2005)

fas Receptor MeSH Descriptor Data 2024