NLM Logo

Fibrillins MeSH Descriptor Data 2022


MeSH Heading
Fibrillins
Tree Number(s)
D09.400.430.875
D12.776.395.341
D12.776.860.300.400
Unique ID
D000071837
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071837
Scope Note
A family of extracellular matrix glycoproteins that is structurally similar to LATENT TGF-BETA BINDING PROTEINS, but contain additional TGF-beta binding domains, in addition to unique domains at their N and C-terminals. Fibrillins assemble into 10-12 nm MICROFIBRILS that function in a variety of cell interactions with the EXTRACELLULAR MATRIX and developmental processes such as ELASTIC TISSUE maintenance and assembly, and the targeting of growth factors to the extracellular matrix.
Entry Term(s)
Fibrillin
Registry Number
0
Public MeSH Note
2017; see FIBRILLIN 1985-2016
History Note
2017; use FIBRILLIN 1985-2016
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/04/15
Fibrillins Preferred
page delivered in 0.16s