MeSH Browser

MeSH Heading: Trichosanthin
Tree Number(s): D12.776.765.710.500.500
Unique ID: D015978
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015978
Annotation: /drug eff /‌ultrastruct permitted
Scope Note: Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS.
Entry Term(s): Compound Q; GLQ-223; GLQ223; T'ien-hua-fen; Tian-hua-fen; alpha-Trichosanthin
Pharm Action: Abortifacient Agents, Nonsteroidal
Antineoplastic Agents, Phytogenic
Anti-HIV Agents
Registry Number: 60318-52-7
CAS Type 1 Name: Proteins, specific or class, trichosanthins
Previous Indexing: Abortifacient Agents, Non-Steroidal (1977-1989); Plant Proteins (1976-1989)
Public MeSH Note: 90
History Note: 90
Date Established: 1990/01/01
Date of Entry: 1989/05/25
Revision Date: 2007/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024413
Registry Number: 60318-52-7
Scope Note: Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS.
Terms: Trichosanthin Preferred Term
Term UI T047398
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1990); alpha-Trichosanthin
Term UI T047394
Date05/04/1989
LexicalTag NON
ThesaurusID NLM (1990); Compound Q
Term UI T047395
Date05/04/1989
LexicalTag NON
ThesaurusID NLM (1990)

Trichosanthin MeSH Descriptor Data 2024