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Ribosome Inactivating Proteins MeSH Descriptor Data 2022


MeSH Heading
Ribosome Inactivating Proteins
Tree Number(s)
D08.811.277.450.430.700
D12.776.765.710
Unique ID
D054788
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D054788
Scope Note
N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity.
Entry Term(s)
Polynucleotide Adenosine Glycosidase
RIP (Ribosome Inactivating Proteins)
RIP Ribosome Inactivating Proteins
RNA Glycosylase
RNA N-Glycosidase
rRNA N-Glycosylases
Pharm Action
Protein Synthesis Inhibitors
Registry Number
EC 3.2.2.22
Previous Indexing
N-Glycosyl Hydrolases (1988-2007)
Public MeSH Note
2008; RNA N-GLYCOSIDASE was indexed under N-GLYCOSYL HYDROLASES 1988-2007
History Note
2008(1988)
Date Established
2008/01/01
Date of Entry
2007/07/09
Revision Date
2021/06/30
Ribosome Inactivating Proteins Preferred
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