NLM Logo

Trichosanthin MeSH Descriptor Data 2022


MeSH Heading
Trichosanthin
Tree Number(s)
D12.776.765.710.500.500
Unique ID
D015978
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D015978
Annotation
/drug eff /‌ultrastruct permitted
Scope Note
Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS.
Entry Term(s)
Compound Q
GLQ-223
GLQ223
T'ien-hua-fen
Tian-hua-fen
alpha-Trichosanthin
Pharm Action
Abortifacient Agents, Nonsteroidal
Antineoplastic Agents, Phytogenic
Anti-HIV Agents
Registry Number
60318-52-7
CAS Type 1 Name
Proteins, specific or class, trichosanthins
Previous Indexing
Abortifacient Agents, Non-Steroidal (1977-1989)
Plant Proteins (1976-1989)
Public MeSH Note
90
History Note
90
Date Established
1990/01/01
Date of Entry
1989/05/25
Revision Date
2007/07/09
Trichosanthin Preferred
Tian-hua-fen Related
GLQ-223 Narrower
page delivered in 0.135s