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Pregnancy-Associated alpha 2-Macroglobulins MeSH Descriptor Data 2025
Large (>160 kDa) glycoproteins with electrophoretic mobility of ALPHA-GLOBULINS, found in high concentration in the plasma of PREGNANT PEOPLE but also in a number of species including mouse, rat, and others (ALPHA-MACROGLOBULINS). In humans, they are always present in the circulation and are nonspecific inhibitors of PROTEINASES, similar to COMPLEMENT PROTEINS (C3; C4; C5).
Entry Version
PREGN ASSOCIATED ALPHA 2 MACROGLOBULINS
Entry Term(s)
PAAG
Pregnancy-Associated alpha 2-Globulins
Pregnancy-Associated alpha 2-Glycoproteins
alpha 2-Glucoprotein
alpha 2-Glucoproteins
alpha 2-Macroglobulin
alpha(2)-PAG
alpha2-Macroglobulin
alpha2-PAG
Registry Numbers
0
Previous Indexing
alpha-Macroglobulins (1976-2003)
Public MeSH Note
2004; see PREGNANCY ZONE PROTEINS 1980-2003; for ALPHA 2-GLUCOPROTEINS see ALPHA-MACROGLOBULINS 1976-2017
History Note
2018 (2004); for ALPHA 2-GLUCOPROTEINS use ALPHA-MACROGLOBULINS 1976-2017
Large (>160 kDa) glycoproteins with electrophoretic mobility of ALPHA-GLOBULINS, found in high concentration in the plasma of PREGNANT PEOPLE but also in a number of species including mouse, rat, and others (ALPHA-MACROGLOBULINS). In humans, they are always present in the circulation and are nonspecific inhibitors of PROTEINASES, similar to COMPLEMENT PROTEINS (C3; C4; C5).