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Placenta Growth Factor MeSH Descriptor Data 2022


MeSH Heading
Placenta Growth Factor
Tree Number(s)
D12.644.276.100.800.100
D12.776.780.551
Unique ID
D000072483
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072483
Scope Note
An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.
Entry Term(s)
Placenta Growth Factor, PLGF-1 Isoform
Placenta Growth Factor, PLGF-2 Isoform
Placenta Growth Factor, PLGF-3 Isoform
Placenta Growth Factor, PLGF-4 Isoform
Registry Number
144589-93-5
Public MeSH Note
2017; PLACENTA GROWTH FACTOR was indexed under PREGNANCY PROTEINS 1991-2016
History Note
2017 (1991)
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/07/05
Placenta Growth Factor Preferred
Placenta Growth Factor, PLGF-1 Isoform Narrower
Placenta Growth Factor, PLGF-3 Isoform Narrower
Placenta Growth Factor, PLGF-4 Isoform Broader
Placenta Growth Factor, PLGF-2 Isoform Narrower
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