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A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.
Entry Term(s)
Anemia, Cooley's
Anemia, Erythroblastic
Anemia, Mediterranean
Erythroblastic Anemia
Hemoglobin F Disease
Mediterranean Anemia
Microcytemia, beta Type
Thalassemia Intermedia
Thalassemia Major
Thalassemia Major (beta-Thalassemia Major)
Thalassemia Minor
Thalassemia Minor (beta-Thalassemia Minor)
Thalassemia, beta Type
beta Thalassemia
NLM Classification #
WH 170
Previous Indexing
Thalassemia (1966-1992)
Public MeSH Note
93; was see THALASSEMIA 1988-92; ANEMIA, ERYTHROBLASTIC was see THALASSEMIA 1965-92, was heading 1963-64; ANEMIA, COOLEY'S was see THALASSEMIA 1963-92; ANEMIA, MEDITERRANEAN was see THALASSEMIA 1965-92; HEMOGLOBIN F DISEASE & THALASSEMIA MAJOR were see THALASSEMIA 1988-92
Online Note
use THALASSEMIA to search ANEMIA, ERYTHROBLASTIC & ANEMIA, COOLEY'S & ANEMIA, MEDITERRANEAN 1966-92 and HEMOGLOBIN F DISEASE & THALASSEMIA MAJOR 1988-92
History Note
93; was see THALASSEMIA 1988-92; ANEMIA, ERYTHROBLASTIC was see THALASSEMIA 1965-92, was heading 1963-64; ANEMIA, COOLEY'S was see THALASSEMIA 1963-92; ANEMIA, MEDITERRANEAN was see THALASSEMIA 1965-92; HEMOGLOBIN F DISEASE & THALASSEMIA MAJOR were see THALASSEMIA 1988-92
A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.