MeSH Browser

MeSH Heading: beta-Thalassemia
Tree Number(s): C15.378.050.141.150.875.150; C15.378.420.826.150; C16.320.070.875.150; C16.320.365.826.150
Unique ID: D017086
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D017086
Annotation: delta-beta thalassemia = DELTA-THALASSEMIA + BETA-THALASSEMIA
Scope Note: A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.
Entry Term(s): Anemia, Cooley's; Anemia, Erythroblastic; Anemia, Mediterranean; Erythroblastic Anemia; Hemoglobin F Disease; Mediterranean Anemia; Microcytemia, beta Type; Thalassemia Intermedia; Thalassemia Major; Thalassemia Major (beta-Thalassemia Major); Thalassemia Minor; Thalassemia Minor (beta-Thalassemia Minor); Thalassemia, beta Type; beta Thalassemia
NLM Classification #: WH 170
Previous Indexing: Thalassemia (1966-1992)
Public MeSH Note: 93; was see THALASSEMIA 1988-92; ANEMIA, ERYTHROBLASTIC was see THALASSEMIA 1965-92, was heading 1963-64; ANEMIA, COOLEY'S was see THALASSEMIA 1963-92; ANEMIA, MEDITERRANEAN was see THALASSEMIA 1965-92; HEMOGLOBIN F DISEASE & THALASSEMIA MAJOR were see THALASSEMIA 1988-92
Online Note: use THALASSEMIA to search ANEMIA, ERYTHROBLASTIC & ANEMIA, COOLEY'S & ANEMIA, MEDITERRANEAN 1966-92 and HEMOGLOBIN F DISEASE & THALASSEMIA MAJOR 1988-92
History Note: 93; was see THALASSEMIA 1988-92; ANEMIA, ERYTHROBLASTIC was see THALASSEMIA 1965-92, was heading 1963-64; ANEMIA, COOLEY'S was see THALASSEMIA 1963-92; ANEMIA, MEDITERRANEAN was see THALASSEMIA 1965-92; HEMOGLOBIN F DISEASE & THALASSEMIA MAJOR were see THALASSEMIA 1988-92
Date Established: 1993/01/01
Date of Entry: 1992/05/07
Revision Date: 2023/02/26

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
  - Anemia [C15.378.050]
    - Anemia, Hemolytic [C15.378.050.141]
      - Anemia, Hemolytic, Congenital [C15.378.050.141.150]
        
        Thalassemia [C15.378.050.141.150.875]
        
        alpha-Thalassemia [C15.378.050.141.150.875.100]
        
        beta-Thalassemia [C15.378.050.141.150.875.150]
        
        delta-Thalassemia [C15.378.050.141.150.875.575]

Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
  - Hemoglobinopathies [C15.378.420]
    - Thalassemia [C15.378.420.826]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Anemia, Hemolytic, Congenital [C16.320.070]
    - Thalassemia [C16.320.070.875]

Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
  - Hemoglobinopathies [C16.320.365]
    - Thalassemia [C16.320.365.826]

beta-Thalassemia Preferred

Concept UI: M0025960
Scope Note: A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.
Terms: beta-Thalassemia Preferred Term
Term UI T051011
Date01/01/1999
LexicalTag NON
ThesaurusID; Thalassemia, beta Type
Term UI T846073
Date06/24/2013
LexicalTag NON
ThesaurusID GHR (2014); beta Thalassemia
Term UI T846072
Date06/24/2013
LexicalTag NON
ThesaurusID GHR (2014); Microcytemia, beta Type
Term UI T846074
Date06/24/2013
LexicalTag NON
ThesaurusID GHR (2014)

Thalassemia Minor Narrower

Thalassemia Major Narrower

Concept UI: M0025959
Terms: Thalassemia Major Preferred Term
Term UI T051010
Date09/26/1991
LexicalTag NON
ThesaurusID NLM (1993); Erythroblastic Anemia
Term UI T846076
Date06/24/2013
LexicalTag NON
ThesaurusID GHR (2014); Anemia, Cooley's
Term UI T051007
Date09/26/1991
LexicalTag EPO
ThesaurusID; Thalassemia Major (beta-Thalassemia Major)
Term UI T764010
Date01/13/2010
LexicalTag NON
ThesaurusID NLM (2011); Anemia, Mediterranean
Term UI T051009
Date09/26/1991
LexicalTag EPO
ThesaurusID; Mediterranean Anemia
Term UI T846075
Date06/24/2013
LexicalTag NON
ThesaurusID GHR (2014); Anemia, Erythroblastic
Term UI T051008
Date09/26/1991
LexicalTag NON
ThesaurusID

Hemoglobin F Disease Narrower

Thalassemia Intermedia Narrower

beta-Thalassemia MeSH Descriptor Data 2024