MeSH Browser

MeSH Heading: HIV Envelope Protein gp41
Tree Number(s): D12.776.543.512.500.330; D12.776.964.350.520.330; D12.776.964.775.325.164.200; D12.776.964.775.562.500.200; D12.776.964.970.880.325.164.200; D12.776.964.970.880.910.330; D23.050.327.520.330
Unique ID: D015700
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D015700
Scope Note: Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. It has a molecular weight of 41,000 and is glycosylated. The N-terminal part of gp41 is thought to be involved in CELL FUSION with the CD4 ANTIGENS of T4 LYMPHOCYTES, leading to syncytial formation. Gp41 is one of the most common HIV antigens detected by IMMUNOBLOTTING.
Entry Term(s): Envelope Protein gp41, HIV; HIV Transmembrane Protein gp41; HTLV-III gp41; env Protein gp41, HIV; gp41 Envelope Protein, HIV; gp41(HIV)
Registry Numbers: 0
NLM Classification #: WC 503
Previous Indexing: Retroviridae Proteins (1986-1989); Viral Envelope Proteins (1983-1989)
Public MeSH Note: 90
History Note: 90
Date Established: 1990/01/01
Date of Entry: 1989/06/19
Revision Date: 2022/04/13

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024085
Registry Numbers: 0
Scope Note: Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. It has a molecular weight of 41,000 and is glycosylated. The N-terminal part of gp41 is thought to be involved in CELL FUSION with the CD4 ANTIGENS of T4 LYMPHOCYTES, leading to syncytial formation. Gp41 is one of the most common HIV antigens detected by IMMUNOBLOTTING.
Terms: HIV Envelope Protein gp41 Preferred Term
Term UI T046543
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1990); HIV Transmembrane Protein gp41
Term UI T046544
Date02/14/1989
LexicalTag ABX
ThesaurusID NLM (1990); Envelope Protein gp41, HIV
Term UI T046542
Date02/14/1989
LexicalTag ABX
ThesaurusID NLM (1990); env Protein gp41, HIV
Term UI T046539
Date06/19/1989
LexicalTag ABX
ThesaurusID NLM (1990); gp41(HIV)
Term UI T046540
Date05/25/1989
LexicalTag ABB
ThesaurusID NLM (1990); gp41 Envelope Protein, HIV
Term UI T046541
Date02/14/1989
LexicalTag ABX
ThesaurusID NLM (1990); HTLV-III gp41
Term UI T046546
Date02/14/1989
LexicalTag ABB
ThesaurusID NLM (1990)

HIV Envelope Protein gp41 MeSH Descriptor Data 2025